NFATC2/NFAT1 Antibody

Images

 
Western Blot: NFAT1 Antibody [NBP1-69219] - Titration: 0.2-1 ug/ml, Positive Control: Hela cell lysate.
Immunohistochemistry-Paraffin: NFAT1 Antibody [NBP1-69219] - Human thymus tissue at an antibody concentration of 5ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-69219
    • Availability
      Product Discontinued

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NFATC2/NFAT1 Antibody Summary

Immunogen
Synthetic peptides corresponding to NFATC2 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2) The peptide sequence was selected from the C terminal of NFATC2. Peptide sequence PTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQ
Clonality
Polyclonal
Host
Rabbit
Gene
NFATC2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This is a rabbit polyclonal antibody against NFATC2 and was validated on Western blot.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS & 2% Sucrose.
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for NFATC2/NFAT1 Antibody

  • NFAT pre-existing subunit
  • NFAT transcription complex, preexisting component
  • NFAT1
  • NFAT1nuclear factor of activated T-cells, cytoplasmic 2
  • NFATC2
  • NF-ATc2
  • NFATP
  • NF-ATp
  • NFATPnuclear factor of activated T-cells, preexisting component
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • preexisting nuclear factor of activated T-cells 2
  • T cell transcription factor NFAT1
  • T-cell transcription factor NFAT1

Background

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NFATC2
Entrez
Uniprot