Neurogenin-1 Antibody (309707) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB
• Clone: 309707
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Neurogenin-1 Antibody (309707) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human Neurogenin‑1
  Ala145-His237
  Accession # NP_006152
• Specificity: Detects human Neurogenin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Neurogenin-3 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neurogenin-1 Antibody (309707) [Alexa Fluor® 647]

• AKA
• BHLHA6
• bHLHa6NGN-1
• Class A basic helix-loop-helix protein 6
• Math4C
• NEUROD3
• NEUROD3neurogenic differentiation 3
• NEUROG1
• Neurogenic basic-helix-loop-helix protein
• Neurogenic differentiation factor 3
• neurogenin 1
• Neurogenin1
• Neurogenin-1
• NGN
• ngn1

Background

Neurogenin-1 is a 26 kDa developmentally expressed nuclear protein of the basic helix-loop-helix (bHLH) family, class B subfamily. bHLH proteins are transcription factors that form dimers to bind DNA. NGN1 is expressed only in embryonic neural tissue and supports neuronal differentiation but inhibits glial cell differentiation. Human Neurogenin-1 shows 93% amino acid identity with both mouse and rat Neurogenin-1 over the sequence used as an immunogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.