Neuritin Antibody (79537) [Alexa Fluor® 647]

HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human Neuritin Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB283R, filled histogram) or isotype control antibody (Catalog # IC0041R, open histogram). View our protocol for Staining Membrane-associated Proteins.

Product Discontinued

Neuritin Antibody (79537) [Alexa Fluor® 647] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Neuritin
  Ala28-Gly114
  Accession # Q9NPD7
• Specificity: Detects human Neuritin in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse Neuritin.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: NRN1
• Purity Statement: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 5 uL/10^6 cells
• Application Notes: Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide
• Concentration: Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuritin Antibody (79537) [Alexa Fluor® 647]

• dJ380B8.2
• neuritin 1
• Neuritin
• NRN1
• NRNMGC44811

Background

Neuritin (NRN1) is a 14 kDa GPI-linked molecule that is expressed on developing and differentiating neurons, as well as hepatocytes and Schwann cells. Neuritin is upregulated in response to BDNF, NT-3, androgens, and hypoxia, and it promotes neuronal migration, neurite extension, and arborization. Neuritin does contribute to the formation of the ionotrophic glutamate receptor APMA. Here, it is a component of the outer core. Mature human Neuritin shares 99% and 100% amino acid sequence identity with mouse and rat Neuritin, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NRN1
• Uniprot:
  • Q9NPD7()