Neuregulin-2 Antibody (3D2)

Images

 
Western Blot: Neuregulin-2 Antibody (3D2) [H00009542-M01] - NRG2 monoclonal antibody (M01), clone 3D2. Analysis of NRG2 expression in human pancreas.
Sandwich ELISA: Neuregulin-2 Antibody (3D2) [H00009542-M01] - Detection limit for recombinant GST tagged NRG2 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
3D2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Neuregulin-2 Antibody (3D2) Summary

Immunogen
NRG2 (NP_004874, 116 a.a. ~ 216 a.a) partial recombinant protein with GST tag.SLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCVPLERNQRYIFFLEPTEQPLVFKTAFAPLD
Specificity
NRG2 - neuregulin 2
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NRG2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA 1:100-1:2000
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Publications
Read Publication using H00009542-M01.

Reactivity Notes

Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Neuregulin-2 Antibody (3D2)

  • divergent of neuregulin-1
  • DON1
  • Don-1
  • HRG2
  • neuregulin 2
  • NTAKneural- and thymus-derived activator for ErbB kinases
  • pro-neuregulin-2, membrane-bound isoform
  • pro-NRG2

Background

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcripts encoding distinct isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Neuregulin-2 Antibody (H00009542-M01)(1)

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Bioinformatics

Gene Symbol NRG2
Entrez
OMIM
Uniprot