Neuregulin-2 Antibody (3D2) - Azide and BSA Free

Western Blot: Neuregulin-2 Antibody (3D2) [H00009542-M01] - NRG2 monoclonal antibody (M01), clone 3D2. Analysis of NRG2 expression in human pancreas.

ELISA: Neuregulin-2 Antibody (3D2) [H00009542-M01] - Detection limit for recombinant GST tagged NRG2 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 3D2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Neuregulin-2 Antibody (3D2) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse Neuregulin-2 Antibody (3D2) - Azide and BSA Free (H00009542-M01) is a monoclonal antibody validated for use in WB and ELISA. Anti-Neuregulin-2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: NRG2 (NP_004874, 116 a.a. ~ 215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCVPLERNQRYIFFLEPTEQPLVFKTAFAPLD
• Specificity: NRG2 - neuregulin 2
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: NRG2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Neuregulin-2 Antibody (3D2) - Azide and BSA Free

• divergent of neuregulin-1
• DON1
• Don-1
• HRG2
• neuregulin 2
• Neuregulin2
• Neuregulin-2
• NRG2
• NTAK
• NTAKneural- and thymus-derived activator for ErbB kinases
• pro-neuregulin-2, membrane-bound isoform
• pro-NRG2

Background

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcripts encoding distinct isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Neuregulin-2 Antibody (H00009542-M01)(1)

Publication using H00009542-M01

• Frogne T, Benjaminsen RV, Sonne-Hansen K et al. Activation of ErbB3, EGFR Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant. Breast Cancer Res Treat. 2008-04-14 [PMID: 18409071]

Bioinformatics

• Gene Symbol: NRG2
• Entrez:
  • 9542(Human)
• OMIM:
  • 603818(Human)
• Uniprot:
  • NP_004874(Human)