NEIL1 Antibody (OTI1D1) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Applications: WB
• Clone: OTI1D1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

NEIL1 Antibody (OTI1D1) [Alexa Fluor™ Plus 647] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 186-390 of human NEIL1 (NP_078884) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: NEIL1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NEIL1 Antibody (OTI1D1) [Alexa Fluor™ Plus 647]

• DNA-(apurinic or apyrimidinic site) lyase Neil1
• EC 3.2.2.-
• EC 4.2.99.18
• endonuclease 8-like 1
• endonuclease VIII
• Endonuclease VIII-like 1
• FLJ22402
• FPG1DNA glycosylase/AP lyase Neil1
• hFPG1
• NEH1
• nei endonuclease VIII-like 1 (E. coli)
• Nei homolog 1
• NEI1
• Nei-like protein 1

Background

NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NEIL1