NCBP1 Antibody [Janelia Fluor® 549]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 549

NCBP1 Antibody [Janelia Fluor® 549] Summary

• Immunogen: Antibody was raised against a 17 amino acid peptide near the center of human NCBP1. The immunogen is located within amino acids 420 - 470 of NCBP1. Amino Acid Squence: LSQDPESPKPKFVREV
• Specificity: At least two isoforms of NCBP1 are known to exist; this antibody will detect both isoforms of NCBP1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NCBP1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (81%)

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for NCBP1 Antibody [Janelia Fluor® 549]

• CBP80nuclear cap binding protein subunit 1, 80kD
• NCBP 80 kDa subunit
• NCBPMGC2087
• nuclear cap binding protein subunit 1, 80kDa
• nuclear cap-binding protein subunit 1,80 kDa nuclear cap-binding protein
• Sto1

Background

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NCBP1