Western Blot: RENT1/UPF1/hUPF1 Antibody [NB100-368] - Samples: Whole cell lysate (50 ug) from HeLa and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified goat anti-RENT1 antibody used for ...read more
Western Blot: RENT1/UPF1/hUPF1 Antibody [NB100-368] - Whole cell lysate (30 ug) from lymphoblastoid cell lines (EBV-immotalized B-cell from a normal individual). Antibody used at 1 ug/ml.
The immunogen recognized by this antibody maps to a region between residue 250 and 300 of human Regulator of Nonsense Transcripts 1 (up-frameshift mutation 1 homolog) using the numbering given in entry NP_002902.2 (GeneID 5976).
Immunogen affinity purified
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UPF1 regulator of nonsense transcripts homolog (yeast)
up-frameshift mutation 1 homolog
Up-frameshift suppressor 1 homolog
yeast Upf1p homolog
RENT1 (regulator of nonsense transcripts 1) is a group 1 RNA helicase, RNA-binding protein whose RNA-binding activity is modulated by ATP. It enters the nucleus where it influences early events in mRNA biogenesis. It functions in NMD (non-sense-mediated mRNA decay) in mammalian cells, ridding cells of aberrant mRNAs containing premature termination codons.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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