Home » NCAM-1/CD56 » NCAM-1/CD56 Antibodies » NCAM-1/CD56 Antibody (C5.9) [PE]

NCAM-1/CD56 Antibody (C5.9) [PE]

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Summary
Product Discontinued
View other related NCAM-1/CD56 Primary Antibodies

Order Details


    • Catalog Number
      NB100-63939
    • Availability
      Product Discontinued

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NCAM-1/CD56 Antibody (C5.9) [PE] Summary

Immunogen
Made to Human CD56
Specificity
Recognises the human CD56 cell surface antigen, NKH-1, expressed by natural killer cells.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
NCAM1
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Control
NCAM-1/CD56 Overexpression Lysate

Reactivity Notes

Cross reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
IgG purified

Alternate Names for NCAM-1/CD56 Antibody (C5.9) [PE]

  • CD56 / NCAM-1
  • CD56 antigen
  • CD56
  • MSK39
  • NCAM1
  • N-CAM-1
  • NCAM-1
  • NCAMantigen recognized by monoclonal 5.1H11
  • neural cell adhesion molecule 1
  • neural cell adhesion molecule, NCAM

Background

CD56, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of CD56 consists of five of these Ig domains and two fibronectin type III homology regions. CD56 is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of CD56. Through its extracellular region, CD56 mediates homophilic interactions. In addition, CD56 can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NCAM-1/CD56
Antibody (C5.9) [PE]
NB100-63939
NCAM-1/CD56 Antibody (C5.9) [PE]
Species: Hu
Applications: Flow

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Control Lysate(s)

NCAM-1/CD56 Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NCAM1