n-Myc Antibody (PCRP-MYCN-1A9)

Flow cytometric analysis of PFA-fixed HeLa cells.n-Myc Antibody (PCRP-MYCN-1A9) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).

Analysis of Protein Array containing more than 19,000 full-length human proteins usingn-Myc Antibody (PCRP-MYCN-1A9).

• Reactivity: Hu
• Applications: ELISA, Flow
• Clone: PCRP-MYCN-1A9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

n-Myc Antibody (PCRP-MYCN-1A9) Summary

• Description: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.
• Immunogen: Recombinant protein domain (around aa335-463) of human n-Myc protein
• Localization: Nucleus
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MYCN
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry 1-2ug/million cells
• Application Notes: ELISA: For coating, order antibody without BSA. Optimal dilution for a specific application should be determined.

Reactivity Notes

Predicted to react with rat.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for n-Myc Antibody (PCRP-MYCN-1A9)

• BHLHE37
• bHLHe37N-myc proto-oncogene protein
• Class E basic helix-loop-helix protein 37
• MODED
• neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
• N-myc
• NMYCneuroblastoma MYC oncogene
• ODED
• oncogene NMYC
• pp65/67
• v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
• v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Background

n-Myc is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYCN