N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - Azide and BSA Free

Western Blot: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [H00002588-B01P] - Analysis of GALNS expression in transfected 293T cell line by GALNS polyclonal antibody. Lane1:GALNS transfected lysate(57.42 KDa). Lane2:Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: GALNS (NP_000503.1, 1 a.a. - 522 a.a.) full-length human protein. MAAVVAATRWWQLLLVLSAAGMGASGAPQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH
• Specificity: GALNS - galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: GALNS
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - Azide and BSA Free

• Chondroitinase
• Chondroitinsulfatase
• EC 3.1.6
• EC 3.1.6.4
• FLJ17434
• FLJ42844
• FLJ98217
• GA6S
• galactosamine (N-acetyl)-6-sulfate sulfatase
• Galactose-6-Sulfate Sulfatase
• GalNAc6S Sulfatase
• GALNAC6S
• GALNS
• GAS
• MPS4A
• NAcetylgalactosamine6Sulfatase
• N-Acetylgalactosamine-6-Sulfatase
• N-acetylgalactosamine-6-sulfate sulfatase

Background

This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALNS
• Entrez:
  • 2588(Human)
• Uniprot:
  • NP_000503.1(Human)