Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free

• Reactivity: Hu, Rt, Rb
• Applications: ELISA, ICC/IF, IHC
• Clone: TH81 (BGN/04/4481)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free Summary

• Description: Novus Biologicals Mouse Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free (NB100-65675) is a monoclonal antibody validated for use in IHC, ELISA and ICC/IF. Anti-Myosin heavy chain 2 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Myosin heavy chain from rabbit muscle
• Localization: Cytoplasm, myofibril. Note: thick filaments of the myofibrils.
• Specificity: NB100-65675 reacts strongly with human cardiac myosin and also recognizes rabbit myosin heavy and light chains.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MYH2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free

• fast 2a myosin heavy chain
• MYH2
• MYH2A
• MYHas8
• MyHC-2a
• MyHC-IIa
• MYHSA2
• Myosin heavy chain 2
• myosin heavy chain 2a
• myosin heavy chain IIa
• myosin, heavy chain 2, skeletal muscle, adult
• myosin, heavy polypeptide 2, skeletal muscle, adult
• myosin-2
• skeletal muscle, adult 2
• type IIA myosin heavy chain

Background

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Myosin heavy chain 2 Antibody (NB100-65675)(2)

Publications using NB100-65675

• Fang Liu, Zhun Liu, Weisheng Cheng, Qingquan Zhao, Xinyu Zhang, He Zhang, Miao Yu, He Xu, Yichen Gao, Qianrui Jiang, Guojun Shi, Likun Wang, Shanshan Gu, Jia Wang, Nan Cao, Zhongyan Chen The PERK Branch of the Unfolded Protein Response Safeguards Protein Homeostasis and Mesendoderm Specification of Human Pluripotent Stem Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023-12-22 [PMID: 37890465]
• Gomi T, Imamura T. Comprehensive histological investigation of age-related changes in dermal extracellular matrix and muscle fibers in the upper lip vermilion International Journal of Cosmetic Science 2020-08-01 [PMID: 32274802] (Immunocytochemistry/ Immunofluorescence)

Bioinformatics

• Gene Symbol: MYH2
• Entrez:
  • 4620(Human)