MuRF1/TRIM63 Antibody [HRP]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: HRP

MuRF1/TRIM63 Antibody [HRP] Summary

• Immunogen: E. coli-derived recombinant human MuRF1/TRIM63
  Met1-Gly325
  Accession # Q969Q1
• Specificity: Detects human, mouse, and rat MuRF1/TRIM63 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TRIM63
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for MuRF1/TRIM63 Antibody [HRP]

• EC 6.3.2.-
• IRF
• IRFMURF2
• Iris RING finger protein
• MuRF1
• MuRF-1
• muscle specific ring finger protein 2
• Muscle-specific RING finger protein 1
• RING finger protein 28FLJ32380
• RNF28
• RNF28E3 ubiquitin-protein ligase TRIM63
• SMRZ
• SMRZMURF-1
• Striated muscle RING zinc finger protein
• TRIM63
• tripartite motif containing 63
• tripartite motif-containing 63
• Tripartite motif-containing protein 63

Background

MURF1 encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRIM63