MUC5AC Antibody (MUC5AC/917 + 45M1) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
MUC5AC/917 + 45M1
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 532

Order Details

MUC5AC Antibody (MUC5AC/917 + 45M1) [Alexa Fluor® 532] Summary

Immunogen
Recombinant human MUC5AC protein (MUC5AC/917); M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient (45M1)
Localization
Cytoplasmic
Specificity
Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
MUC5AC
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MUC5AC Antibody (MUC5AC/917 + 45M1) [Alexa Fluor® 532]

  • gastric mucin
  • leB
  • lewis B blood group antigen
  • major airway glycoprotein
  • MUC5
  • mucin 5, subtypes A and C, tracheobronchial/gastric
  • mucin 5AC, oligomeric mucus/gel-forming pseudogene
  • mucin 5AC, oligomeric mucus/gel-forming
  • mucin-5 subtype AC, tracheobronchial
  • mucin-5AC
  • TBM
  • tracheobronchial mucin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47696AF350
Alexa Fluor 405 NBP2-47696AF405
Alexa Fluor 488 NBP2-47696AF488
Alexa Fluor 532 NBP2-47696AF532
Alexa Fluor 594 NBP2-47696AF594
Alexa Fluor 647 NBP2-47696AF647
Alexa Fluor 700 NBP2-47696AF700
Alexa Fluor 750 NBP2-47696AF750
Allophycocyanin NBP2-47696APC
Allophycocyanin/Cy7 NBP2-47696APCCY7
Biotin NBP2-47696B
DyLight 350 NBP2-47696UV
DyLight 405 NBP2-47696V
DyLight 488 NBP2-47696G
DyLight 550 NBP2-47696R
DyLight 594 NBP2-47696DL594
DyLight 650 NBP2-47696C
DyLight 680 NBP2-47696FR
DyLight 755 NBP2-47696IR
FITC NBP2-47696F
HRP NBP2-47696H
Janelia Fluor 549 NBP2-47696JF549
Janelia Fluor 646 NBP2-47696JF646
PE NBP2-47696PE
PE/Atto594 NBP2-47696PEATT594
PE/Cy5.5 NBP2-47696PECY55
PE/Cy7 NBP2-47696PECY7
PerCP NBP2-47696PCP

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Bioinformatics

Gene Symbol MUC5AC