MSPR/Ron [p Tyr1238, p Tyr1239, p Tyr1239] Antibody [Unconjugated]


Western blot shows lysates of MDA‑MB‑453 human breast cancer cell line untreated (-) or treated (+) with 100 μM pervanadate (PV) for 10 minutes. The membranes were untreated or treated with calf intestinal more
Human Phospho-MSP R/Ron (Y1238/Y1239) was immunoprecipitated from 1 mg of lysates of MDA‑MB‑453 human breast cancer cell line untreated (-) or treated (+) with 100 uM Pervanadate (PV) for 10 minutes or 100 ng/mL more

Product Details

Reactivity HuSpecies Glossary
Applications WB

Order Details

View Available Formulations
Catalog# & Formulation Size Price

MSPR/Ron [p Tyr1238, p Tyr1239, p Tyr1239] Antibody [Unconjugated] Summary

Phosphopeptide containing human MSP R/Ron Y1238/Y1239 sites
p Tyr1239, p Tyr1238, p Tyr1239
The antibody detects endogenous human MSP R/Ron phosphorylated at Y1238/Y1239 using Western blots.
Purity Statement
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1 ug/mL
Read Publications using
AF1947 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSPR/Ron [p Tyr1238, p Tyr1239, p Tyr1239] Antibody [Unconjugated]

  • CD136 antigen
  • CD136
  • CDw136c-met-related tyrosine kinase
  • EC 2.7.10
  • EC
  • macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • MSP R
  • MSP receptor
  • MSPR
  • MST1R
  • p185-Ron
  • Protein-tyrosine kinase 8
  • PTK8 protein tyrosine kinase 8
  • PTK8
  • Ron
  • RONmacrophage-stimulating protein receptor
  • soluble RON variant 1
  • soluble RON variant 2
  • soluble RON variant 3
  • soluble RON variant 4


Macrophage stimulating protein receptor (MSP R), also known as Ron, is one of a small family of receptor tyrosine kinases (RTKs) that also includes human Met and chicken Sea. Each family member is synthesized as a single-chain precursor that is cleaved into a mature disulfide-linked heterodimer composed of an extracellular alpha  chain and a membrane-spanning beta  chain with intrinsic tyrosine kinase activity. MSP R/Ron is overexpressed in a number of primary breast carcinomas and non-small cell lung carcinomas, suggesting a role for this RTK in mammary and lung tumor progression. Phosphorylation of MSP R/Ron at Y1238/Y1239 in the activation loop of the kinase domain is responsible for kinase activity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: BA, BA
Species: Hu
Applications: BA
Species: Hu
Applications: Block, CyTOF-ready, Flow, ICC, IHC, KO, Simple Western, WB
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, S-ELISA, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, KD, WB
Species: Hu
Applications: ELISA
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
Species: Hu, Mu
Applications: ICC/IF, WB
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, ICC, IHC, IP, Simple Western, WB
Species: Hu, Pm, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, WB
Species: Ca, Hu, Pm, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: IHC, Simple Western, WB
Species: Hu
Applications: WB

Publications for MSPR/Ron Antibody (AF1947)(7)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: ICC, IHC, Immunoprecipitation, Western Blot.

Filter By Application
Western Blot
All Applications
Filter By Species
All Species
Showing Publications 1 - 7 of 7.
Publications using AF1947 Applications Species
DM Beauvais, SE Nelson, KM Adams, NA Stueven, O Jung, AC Rapraeger Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression The Journal of Biological Chemistry, 2022-05-13;0(0):102029. 2022-05-13 [PMID: 35569509] (Immunoprecipitation, Human) Immunoprecipitation Human
Q Yu, J Wang, T Li, X Guo, S Ding, X Che, L Zhu, Y Peng, X Xu, G Zou, X Zhang Recepteur d'origine nantais contributes to the development of endometriosis via promoting epithelial-mesenchymal transition of a endometrial epithelial cells Journal of Cellular and Molecular Medicine, 2021-01-06;0(0):. 2021-01-06 [PMID: 33410267] (Western Blot, Human) Western Blot Human
D Dustin, G Gu, AR Beyer, SK Herzog, DG Edwards, H Lin, TL Gonzalez, SL Grimm, C Coarfa, DW Chan, BJ Kim, JP De La O, MJ Ellis, D Liu, S Li, AL Welm, SAW Fuqua RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer British Journal of Cancer, 2020-12-01;0(0):. 2020-12-01 [PMID: 33257837] (Western Blot, Human) Western Blot Human
M Balmaña, F Diniz, T Feijão, CC Barrias, S Mereiter, CA Reis Analysis of the Effect of Increased &alpha2,3-Sialylation on RTK Activation in MKN45 Gastric Cancer Spheroids Treated with Crizotinib Int J Mol Sci, 2020-01-22;21(3):. 2020-01-22 [PMID: 31979110] (ICC, Human) ICC Human
R Graves-Dea, G Bogatcheva, S Rehman, Y Lu, JN Higginboth, B Singh Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer Oncotarget, 2019-02-12;10(13):1320-1333. 2019-02-12 [PMID: 30863492] (Western Blot, Human) Western Blot Human
Ota M, Horiguchi M, Fang V, Shibahara K, Kadota K, Loomis C, Cammer M, Rifkin D Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-beta in gastric tissue. Cancer Res, 2014-03-03;74(9):2642-51. 2014-03-03 [PMID: 24590056] (IHC, Mouse) IHC Mouse
Thobe MN, Gurusamy D, Pathrose P, Waltz SE The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells. Oncogene, 2009-10-19;29(2):214-26. 2009-10-19 [PMID: 19838218] (Western Blot, Human) Western Blot Human

Reviews for MSPR/Ron Antibody (AF1947) (0)

There are no reviews for MSPR/Ron Antibody (AF1947). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for MSPR/Ron Antibody (AF1947) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional MSPR/Ron Products

Bioinformatics Tool for MSPR/Ron Antibody (AF1947)

Discover related pathways, diseases and genes to MSPR/Ron Antibody (AF1947). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for MSPR/Ron Antibody (AF1947)

Discover more about diseases related to MSPR/Ron Antibody (AF1947).

Pathways for MSPR/Ron Antibody (AF1947)

View related products by pathway.

PTMs for MSPR/Ron Antibody (AF1947)

Learn more about PTMs related to MSPR/Ron Antibody (AF1947).

Blogs on MSPR/Ron

There are no specific blogs for MSPR/Ron, but you can read our latest blog posts.
mFlour Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our MSPR/Ron [p Tyr1238, p Tyr1239, p Tyr1239] Antibody [Unconjugated] and receive a gift card or discount.


Gene Symbol MST1R