Novus Biologicals Rabbit MSH2 Antibody - BSA Free (NB100-56428) is a polyclonal antibody validated for use in WB. Anti-MSH2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
A portion of amino acids 550-600 of human MSH2 was used as the immunogen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSH2
Purity
Protein G purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified
Alternate Names for MSH2 Antibody - BSA Free
COCA1
DNA mismatch repair protein Msh2
FCC1
hMSH2
HNPCC
HNPCC1
HNPCC1mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
LCFS2
MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
MutS protein homolog 2
Background
MSH2 is involved in DNA repair as a mismatch repair protein, and mutations of MSH2 are found in approximately 50% of inherited non-polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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