Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit



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Reactivity MuSpecies Glossary
Applications ELISA

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Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit Summary

The Quantikine Mouse TRANCE Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse TRANCE in cell culture supernates and serum. It contains NS0-expressed recombinant mouse TRANCE and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant mouse TRANCE accurately. Results obtained using natural mouse TRANCE showed dose respons...e curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse TRANCE.
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Free natural and recombinant mouse TRANCE
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
Interference observed with 1 or more available related molecules.
Read Publications using MTR00.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit

  • CD254 antigen
  • CD254
  • ODF
  • OPGL
  • Osteoclast differentiation factor
  • Osteoprotegerin ligand
  • RANK L
  • RANKLreceptor activator of nuclear factor kappa B ligand
  • Receptor activator of nuclear factor kappa-B ligand
  • sOdf
  • TNF-related activation-induced cytokine
  • TNFSF11
  • tumor necrosis factor (ligand) superfamily, member 11
  • tumor necrosis factor ligand superfamily member 11


TRANCE (TNF-related activation-induced cytokines), also known as RANK Ligand, OPGL, or ODF, is a TNF superfamily ligand produced by osteoblasts, bone marrow stromal cells, and activated T cells. It signals through RANK and is antagonized by the decoy receptor Osteoprotegerin. TRANCE stimulates bone resorption, is required for osteoclast differentiation, and is associated with the development of osteoporosis, vascular calcification, osteopetrosis, and progestin-induced breast cancer. It also mediates body temperature regulation and is essential for the development of a lactating mammary gland.
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for TRANCE/TNFSF11/RANK L (MTR00)(68)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Transgenic Mouse.

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Showing Publications 1 - 10 of 68. Show All 68 Publications.
Publications using MTR00 Applications Species
Uehara, N;Shibusawa, N;Mikami, Y;Kyumoto-Nakamura, Y;Sonoda, S;Kato, H;Yamaza, T;Kukita, T; Bone metastatic mammary tumor cell-derived extracellular vesicles inhibit osteoblast maturation via JNK signaling Archives of biochemistry and biophysics 2023-12-01 [PMID: 37979903] (Mouse) Mouse
Miyagawa, K;Tenshin, H;Mulcrone, PL;Delgado-Calle, J;Subler, MA;Windle, JJ;Chirgwin, JM;Roodman, GD;Kurihara, N; Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to Pagetic lesion formation JCI insight 2023-06-20 [PMID: 37338990] (Mouse) Mouse
X Gao, X Sun, H Cheng, JJ Ruzbarsky, M Mullen, M Huard, J Huard MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair International Journal of Molecular Sciences, 2023-01-25;24(3):. 2023-01-25 [PMID: 36768718] (Mouse) Mouse
X Gao, X Sun, H Cheng, JJ Ruzbarsky, M Mullen, M Huard, J Huard MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair International Journal of Molecular Sciences, 2023;24(3):. 2023 [PMID: 36768718] (Mouse) Mouse
C Polan, C Brenner, M Herten, G Hilken, F Grabellus, HL Meyer, M Burggraf, M Dudda, W Jahnen-Dec, C Wedemeyer, MD Kauther Increased UHMWPE Particle-Induced Osteolysis in Fetuin-A-Deficient Mice Journal of functional biomaterials, 2023-01-04;14(1):. 2023-01-04 [PMID: 36662077] (Mouse) Mouse
JM Kim, YS Yang, J Xie, O Lee, J Kim, J Hong, B Boldyreff, O Filhol, H Chun, MB Greenblatt, G Gao, JH Shim Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes Cell Death and Differentiation, 2022-02-15;0(0):. 2022-02-15 [PMID: 35169297] (Mouse) Mouse
JJM Junqueira, JD Lourenço, KR da Silva, V Jorgetti, RP Vieira, AA de Araujo, K De Angelis, AT Correia, LHV Alves, IFLC Tibério, AP Barbosa, FDTQDS Lopes Increased bone resorption by long-term cigarette smoke exposure in animal model Heliyon, 2021-12-10;7(12):e08587. 2021-12-10 [PMID: 34977408] (Mouse) Mouse
W Zhao, P Wiedemann, EM Wölfel, M Neven, S Peters, T Imhof, M Koch, B Busse, M Amling, T Schinke, TA Yorgan Decreased Trabecular Bone Mass in Col22a1-Deficient Mice Cells, 2021-11-04;10(11):. 2021-11-04 [PMID: 34831244] (Mouse) Mouse
N Liao, T Koehne, J Tuckermann, I Triviai, M Amling, JP David, T Schinke, J Luther Osteoblast-specific inactivation of p53 results in locally increased bone formation PLoS ONE, 2021-11-18;16(11):e0249894. 2021-11-18 [PMID: 34793446] (Mouse) Mouse
EJ Lee, W Na, MK Kang, YH Kim, DY Kim, H Oh, SI Kim, SY Oh, S Park, K Park, YH Kang Hydroxycoumarin Scopoletin Inhibits Bone Loss through Enhancing Induction of Bone Turnover Markers in a Mouse Model of Type 2 Diabetes Biomedicines, 2021-06-07;9(6):. 2021-06-07 [PMID: 34200167] (Mouse) Mouse
Show All 68 Publications.

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Additional TRANCE/TNFSF11/RANK L Products


The diverse functions of RANKL/TRANCE/TNFSF11
RANKL (also known as TNF-related activation-induced cytokine), or receptor activator of nuclear factor-?B ligand, was first discovered as a key player in the RANKL/RANK/OPG osteoclast formation pathway. Osteoclasts are large multinucleate cells t...  Read full blog post.

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Gene Symbol Tnfsf11