Mouse TRAIL/TNFSF10 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse TRAIL/TNFSF10 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Tnfsf10

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse TRAIL/TNFSF10 DuoSet ELISA, 15 Plate

• Apo-2 ligand
• APO2L
• Apo-2Ltumor necrosis factor (ligand) family, member 10
• APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta
• CD253 antigen
• CD253
• Protein TRAIL
• TL2
• TNF-related apoptosis-inducing ligand
• TNFSF10
• TRAIL
• TRAILTNF-related apoptosis inducing ligand TRAIL
• tumor necrosis factor (ligand) superfamily, member 10
• tumor necrosis factor ligand superfamily member 10

Background

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Human TRAIL shares 65% amino acid sequence identity with mouse TRAIL and is active on mouse cells.

Publications for TRAIL/TNFSF10 (DY1121)(5)

Publications using DY1121

• N Hijaze, M Ledersnaid, E Simanovich, S Kassem, MA Rahat Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors J Leukoc Biol, 2020-11-17;0(0):. 2020-11-17 [PMID: 33205451] (Mouse)
• A Mohebbi, MS Ebrahimzad, S Baghban Ra, M Saeidi, A Tabarraei, SR Mohebbi, S Shirian, A Gorji, A Ghaemi Non-replicating Newcastle Disease Virus as an adjuvant for DNA vaccine enhances antitumor efficacy through the induction of TRAIL and granzyme B expression Virus Res., 2018-12-29;261(0):72-80. 2018-12-29 [PMID: 30599161] (Mouse)
• DM Habiel, AP Moreira, UB Ismailoglu, MP Dunleavy, KA Cavassani, N van Rooije, AL Coelho, CM Hogaboam TRAIL-Dependent Resolution of Pulmonary Fibrosis Mediators Inflamm., 2018-01-24;2018(0):7934362. 2018-01-24 [PMID: 29670467] (Mouse)
• Joerg Mattes TRAIL signaling is pro-inflammatory and pro-viral in a murine model of rhinovirus 1B infection Am. J. Physiol. Lung Cell Mol. Physiol., 2016-11-11;0(0):ajplung.00200. 2016-11-11 [PMID: 27836899] (Mouse)
• Beug S, Tang V, Lacasse E, Cheung H, Beauregard C, Brun J, Nuyens J, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney D, Ilkow C, Le Boeuf F, Bell J, Korneluk R Smac mimetics and innate immune stimuli synergize to promote tumor death. Nat Biotechnol, 2014-01-26;32(2):182-90. 2014-01-26 [PMID: 24463573] (Human)

FAQs for TRAIL/TNFSF10 (DY1121). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Tnfsf10