Mouse sVEGFR1/Flt-1 DuoSet ELISA, 15 Plate Summary
No significant interference observed with available related molecules.
Packaging, Storage & Formulations
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Mouse sVEGFR1/Flt-1 DuoSet ELISA, 15 Plate
EC 2.7.10 EC 188.8.131.52 FLT FLT1 Flt-1 Fms-like tyrosine kinase 1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor) FRT Tyrosine-protein kinase FRT Tyrosine-protein kinase receptor FLT vascular endothelial growth factor receptor 1 Vascular permeability factor receptor VEGF R1 VEGFR1 VEGFR-1 Background
VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
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Applications: CyTOF-ready, Flow, ICC, IHC, WB
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, ICC, IHC, IP, Simple Western, WB
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Publications for VEGFR1/Flt-1 (DY471)(8)
We have publications tested in 2 confirmed species: Mouse, Rat.
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Publications using DY471
N de Alwis, NK Binder, YTM Mangwiro, S Beard, N Pritchard, E Kadife, BR Fato, E Keenan, FC Brownfoot, TJ Kaitu'u-Li, NJ Hannan Actions of Esomeprazole on the Maternal Vasculature in Lean and Obese Pregnant Mice with Impaired Nitric Oxide Synthesis: A Model of Preeclampsia International Journal of Molecular Sciences, 2022;23(15):. 2022 [PMID: 35897759] (Mouse)
S Liong, O Oseghale, EE To, K Brassingto, JR Erlich, R Luong, F Liong, R Brooks, C Martin, S O'Toole, A Vinh, LAJ O'Neill, S Bozinovski, R Vlahos, PC Papagianis, JJ O'Leary, DA Brooks, S Selemidis Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice Proc. Natl. Acad. Sci. U.S.A., 2020;0(0):. 2020 [PMID: 32958663] (Mouse)
RR Zhu, Q Chen, ZB Liu, HG Ruan, QC Wu, XL Zhou Inhibition of the Notch1 pathway induces peripartum cardiomyopathy J. Cell. Mol. Med., 2020;0(0):. 2020 [PMID: 32529705] (Mouse)
DR Addis, JA Lambert, C Ren, S Doran, S Aggarwal, T Jilling, S Matalon Vascular Endothelial Growth Factor-121 Administration Mitigates Halogen Inhalation-Induced Pulmonary Injury and Fetal Growth Restriction in Pregnant Mice J Am Heart Assoc, 2020;9(3):e013238. 2020 [PMID: 32009528] (Mouse)
M Verma, Y Shimizu-Mo, Y Asakura, JP Ennen, J Bosco, Z Zhou, GH Fong, S Josiah, D Keefe, A Asakura Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy PLoS Genet., 2019;15(12):e1008468. 2019 [PMID: 31877123] (Mouse)
JA Lambert, MA Carlisle, A Lam, S Aggarwal, S Doran, C Ren, WE Bradley, L Dell'Itali, N Ambalavana, DA Ford, RP Patel, T Jilling, S Matalon Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice Hypertension, 2017;0(0):. 2017 [PMID: 28607126] (Mouse)
Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Mucosal Immunol, 2015;8(4):896-905. 2015 [PMID: 25492474] (Mouse)
Craici , Iasmina, Wagner , Steven J, Weissgerber , Tracey L, Grande , Joseph P, Garovic , Vesna D Advances in the pathophysiology of pre-eclampsia and related podocyte injury. Kidney Int, 2014;86(2):275-85. 2014 [PMID: 24573315] (Rat)
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