Mouse IL-2 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse IL-2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Il2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-2 DuoSet ELISA, 15 Plate

• Aldesleukin
• IL2
• IL-2
• IL-2lymphokine
• interleukin 2
• interleukin-2
• involved in regulation of T-cell clonal expansion
• Proleukin
• T cell growth factor
• T-cell growth factor
• TCGF

Background

IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c). IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.

Publications for IL-2 (DY402)(90)

Publications using DY402

• Jeong, SH;Jung, J;Park, YJ;Lee, SJ;Lee, SJ; The Influence of polycyclic aromatic hydrocarbons exposure on the gut microbiome composition and inflammatory responses Ecotoxicology and environmental safety 2025-08-21 [PMID: 40848419] (Mouse)
• Das, A;Pramanik, U;Brown, EM;Liu, CY;Gong, H;Fascetti, J;Gibson, M;Stealey, S;Zustiak, SP;Berkland, C;Jackrel, ME;White, MA;Rudra, JS; Substituent-based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides bioRxiv : the preprint server for biology 2025-07-11 [PMID: 40672160] (Mouse)
• Xu, B;Mattapallil, MJ;Jia, X;Tang, J;Horai, R;Caspi, RR;Gery, I; Laquinimod treatment attenuates EAU by inhibiting both the inductive and effector phases in an APC-dependent manner bioRxiv : the preprint server for biology 2025-05-25 [PMID: 40492200] (Mouse)
• Adamowicz, K;Lima Ribeiro, AS;Golda, A;Wadowska, M;Potempa, J;Schmaderer, C;Anders, HJ;Koziel, J;Lech, M; Bidirectional Interaction Between Chronic Kidney Disease and Porphyromonas gingivalis Infection Drives Inflammation and Immune Dysfunction Journal of immunology research 2025-04-17 [PMID: 40276114] (Mouse)
• Chen, K;Han, H;Zhao, S;Xu, B;Yin, B;Lawanprasert, A;Trinidad, M;Burgstone, BW;Murthy, N;Doudna, JA; Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 ribonucleoprotein Nature biotechnology 2024-10-16 [PMID: 39415058] (Mouse)
• Bai, B;Li, T;Zhao, J;Zhao, Y;Zhang, X;Wang, T;Zhang, N;Wang, X;Ba, X;Xu, J;Yu, Y;Wang, B; The Tyrosine Phosphatase Activity of PTPN22 Is Involved in T Cell Development via the Regulation of TCR Expression International journal of molecular sciences 2023-09-25 [PMID: 37833951] (Mouse)
• Mahata, D;Mukherjee, D;Biswas, D;Basak, S;Basak, AJ;Jamir, I;Pandey, N;Khatoon, H;Samanta, D;Basak, A;Mukherjee, G; Activation and differentiation of cognate T cells by a dextran-based antigen-presenting system for cancer immunotherapy European journal of immunology 2023-09-12 [PMID: 37698527] (Mouse)
• Zhao, H;Wu, L;Dai, J;Sun, K;Zi, Z;Guan, J;Zhang, L; Ligand-based adoptive T cell targeting CA125 in ovarian cancer Journal of translational medicine 2023-09-05 [PMID: 37670338] (Mouse)
• Micevic, G;Daniels, A;Flem-Karlsen, K;Park, K;Talty, R;McGeary, M;Mirza, H;Blackburn, HN;Sefik, E;Cheung, JF;Hornick, NI;Aizenbud, L;Joshi, NS;Kluger, H;Iwasaki, A;Bosenberg, MW;Flavell, RA; IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory Proceedings of the National Academy of Sciences of the United States of America 2023-07-25 [PMID: 37459511] (Mouse)
• Shibutani, T;Goto, R;Miyazaki, I;Hashimoto, A;Suzuki, T;Ishida, K;Haruma, T;Osada, T;Harada, T;Fujita, H;Ohkubo, S; Modulation of tumor immune microenvironment by TAS-115, a multi-receptor tyrosine kinase inhibitor, promotes antitumor immunity and contributes anti-PD-1 antibody therapy Scientific reports 2023-05-31 [PMID: 37258621] (Mouse)
• YN Chen, JT Hung, FD Jan, YY Su, JR Hwu, AL Yu, AK Adak, CC Lin Diversity-Oriented Synthesis of a Molecular Library of Immunomodulatory alpha-Galactosylceramides with Fluorous-Tag-Assisted Purification and Evaluation of Their Bioactivities in Regard to IL-2 Secretion Oncogene, 2022-11-02;23(21):. 2022-11-02 [PMID: 36362187] (Mouse)
• T Li, F Tolksdorf, W Sung, H Sato, FJ Eppler, M Hotta, W Kolanus, S Takeoka Arginine-based cationic liposomes accelerate T cell activation and differentiation in vitro International journal of pharmaceutics, 2022-06-15;623(0):121917. 2022-06-15 [PMID: 35714814] (Mouse)
• YH Su, JY Lin Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice International Journal of Molecular Sciences, 2022-04-04;23(7):. 2022-04-04 [PMID: 35409371] (Mouse)
• J Zhu, T Inomata, M Nakamura, K Fujimoto, Y Akasaki, K Fujio, A Yanagawa, K Uchida, J Sung, N Negishi, K Nagino, Y Okumura, M Miura, H Shokirova, M Kuwahara, K Hirosawa, A Midorikawa, A Eguchi, T Huang, H Yagita, S Habu, K Okumura, A Murakami Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model Scientific Reports, 2022-03-22;12(1):4853. 2022-03-22 [PMID: 35318419] (Mouse)
• JY Byun, YT Koh, SY Jang, JW Witcher, JR Chan, A Pustilnik, MJ Daniels, YH Kim, KH Suh, MD Linnik, YM Lee Target modulation and pharmacokinetics/pharmacodynamics translation of the BTK inhibitor poseltinib for model-informed phase II dose selection Scientific Reports, 2021-09-21;11(1):18671. 2021-09-21 [PMID: 34548595] (Mouse)
• R Hiwa, HV Nielsen, JL Mueller, R Mandla, J Zikherman NR4A family members regulate T cell tolerance to preserve immune homeostasis and suppress autoimmunity JCI Insight, 2021-09-08;0(0):. 2021-09-08 [PMID: 34343134] (Mouse)
• A Hickey, P Stamou, S Udayan, A Ramón-Vázq, M Esteban-To, F Bottacini, JA Woznicki, O Hughes, S Melgar, M Ventura, D Van Sinder, V Rossini, K Nally Bifidobacterium breve Exopolysaccharide Blocks Dendritic Cell Maturation and Activation of CD4+ T Cells Frontiers in Microbiology, 2021-06-16;12(0):653587. 2021-06-16 [PMID: 34220742] (Mouse)
• J Zhu, T Inomata, K Fujimoto, K Uchida, K Fujio, K Nagino, M Miura, N Negishi, Y Okumura, Y Akasaki, K Hirosawa, M Kuwahara, A Eguchi, H Shokirova, A Yanagawa, A Midorikawa, A Murakami Ex Vivo-Induced Bone Marrow-Derived Myeloid Suppressor Cells Prevent Corneal Allograft Rejection in Mice Investigative Ophthalmology & Visual Science, 2021-06-01;62(7):3. 2021-06-01 [PMID: 34061951] (Mouse)
• HC Hope, RJ Brownlie, CM Fife, L Steele, M Lorger, RJ Salmond Coordination of asparagine uptake and asparagine synthetase expression modulates CD8+ T cell activation JCI Insight, 2021-05-10;0(0):. 2021-05-10 [PMID: 33822775] (Mouse)
• S Li, K Tajiri, N Murakoshi, D Xu, S Yonebayash, Y Okabe, Z Yuan, D Feng, K Inoue, K Aonuma, Y Shimoda, Z Song, H Mori, H Huang, K Aonuma, M Ieda Programmed Death-Ligand 2 Deficiency Exacerbates Experimental Autoimmune Myocarditis in Mice International Journal of Molecular Sciences, 2021-01-31;22(3):. 2021-01-31 [PMID: 33572655] (Mouse)
• M Aftabizade, YJ Li, Q Zhao, C Zhang, N Ambaye, J Song, T Nagao, C Lahtz, M Fakih, DK Ann, H Yu, A Herrmann Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis JCI Insight, 2021-01-25;6(2):. 2021-01-25 [PMID: 33491667] (Mouse)
• P Tourlomous, JA Wright, AS Bittante, LJ Hopkins, SJ Webster, OJ Bryant, P Mastroeni, DJ Maskell, CE Bryant Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella Nat Microbiol, 2020-10-26;0(0):. 2020-10-26 [PMID: 33106673] (Mouse)
• P Muñoz, M Tristán-Ma, A Sánchez-Gi, G Santilli, A Galy, AJ Thrasher, F Martin WAS Promoter-Driven Lentiviral Vectors Mimic Closely the Lopsided WASP Expression during Megakaryocytic Differentiation Mol Ther Methods Clin Dev, 2020-09-16;19(0):220-235. 2020-09-16 [PMID: 33102615] (Mouse)
• RCA Sainson, AK Thotakura, M Kosmac, G Borhis, N Parveen, R Kimber, J Carvalho, SJ Henderson, KL Pryke, T Okell, S O'Leary, S Ball, C Van Krinks, L Gamand, E Taggart, EJ Pring, H Ali, H Craig, VWY Wong, Q Liang, RJ Rowlands, M Lecointre, J Campbell, I Kirby, D Melvin, V Germaschew, E Oelmann, S Quaratino, M McCourt An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression Cancer Immunology Research, 2020-09-30;8(12):1568-1582. 2020-09-30 [PMID: 32999002] (Mouse)
• S Camorani, M Passariell, L Agnello, S Esposito, F Collina, M Cantile, M Di Bonito, IV Ulasov, M Fedele, A Zannetti, C De Lorenzo, L Cerchia Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer J. Exp. Clin. Cancer Res., 2020-09-07;39(1):180. 2020-09-07 [PMID: 32892748] (Mouse)
• M Passariell, C Vetrei, E Sasso, G Froechlich, C Gentile, AM D'Alise, N Zambrano, E Scarselli, A Nicosia, C De Lorenzo Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells Cancers (Basel), 2020-08-06;12(8):. 2020-08-06 [PMID: 32781690] (Mouse)
• J Shin, OK Kim, S Kim, D Bae, J Lee, J Park, W Jun Immunomodulatory Effect of a Salvia plebeia R. Aqueous Extract in Forced Swimming Exercise-induced Mice Nutrients, 2020-07-28;12(8):. 2020-07-28 [PMID: 32731626] (Mouse)
• H Karimi, H Soleimanja, A Abdoli, RS Banijamali Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: a nanovaccine confer immuneadjuvanting effects to fight cervical cancer Sci Rep, 2020-04-01;10(1):5787. 2020-04-01 [PMID: 32238821] (Mouse)
• TH Yeh, JY Lin Acorus gramineusand and Euodia ruticarpa Steam Distilled Essential Oils Exert Anti-Inflammatory Effects Through Decreasing Th1/Th2 and Pro-/Anti-Inflammatory Cytokine Secretion Ratios In Vitro Biomolecules, 2020-02-19;10(2):. 2020-02-19 [PMID: 32093087] (Mouse)
• NMA Nik Abd Ra, MY Nurliyana, MNFNN Afiqah, MA Osman, M Hamid, MAM Lila Antitumor and antioxidant effects of Clinacanthus nutans Lindau in 4?T1 tumor-bearing mice BMC Complement Altern Med, 2019-11-29;19(1):340. 2019-11-29 [PMID: 31783838] (Mouse)
• G Voisinne, K Kersse, K Chaoui, L Lu, J Chaix, L Zhang, M Goncalves, L Girard, Y Ounoughene, H Wang, O Burlet-Sch, H Luche, F Fiore, M Malissen, A Gonzalez d, Y Liang, R Roncagalli, B Malissen Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics Nat. Immunol., 2019-10-07;0(0):. 2019-10-07 [PMID: 31591574] (Mouse)
• MB Gonzatti, MEP Sousa, AS Tunissi, RA Mortara, AM de Oliveir, NN Pereira Ce, AC Keller Nano spray dryer for vectorizing ?-galactosylceramide in polymeric nanoparticles: A single step process to enhance invariant Natural Killer T lymphocyte responses Int J Pharm, 2019-05-07;565(0):123-132. 2019-05-07 [PMID: 31075434] (Mouse)
• H Leelayuwap, S Ruchirawat, S Boonyaratt Rapid synthesis and immunogenicity of mycobacterial (1?5)-?-d-arabinofuranan Carbohydr Polym, 2018-10-24;206(0):262-272. 2018-10-24 [PMID: 30553321] (Mouse)
• ALS De Souza, S Rudin, R Chang, K Mitchell, T Crandall, S Huang, JK Choi, SL Okitsu, DL Graham, B Tomkinson, T Dellovade ATX-MS-1467 Induces Long-Term Tolerance to Myelin Basic Protein in (DR2?�?Ob1)F1 Mice by Induction of IL-10-Secreting iTregs Neurol Ther, 2018-03-14;0(0):. 2018-03-14 [PMID: 29542041] (Mouse)
• MF Fransen, H Benonisson, WW van Maren, HS Sow, C Breukel, MM Linssen, JWC Claassens, C Brouwers, J van der Ka, M Camps, JW Kleinovink, KK Vonk, S van Heinin, N Klar, L van Beek, V van Harmel, L Daxinger, KS Nandakumar, R Holmdahl, C Coward, Q Lin, S Hirose, D Salvatori, T van Hall, C van Kooten, P Mastroeni, F Ossendorp, JS Verbeek A Restricted Role for Fc?R in the Regulation of Adaptive Immunity J. Immunol., 2018-03-09;0(0):. 2018-03-09 [PMID: 29523656] (Mouse)
• AT Brini, G Amodeo, LM Ferreira, A Milani, S Niada, G Moschetti, S Franchi, E Borsani, LF Rodella, AE Panerai, P Sacerdote Therapeutic effect of human adipose-derived stem cells and their secretome in experimental diabetic pain Sci Rep, 2017-08-29;7(1):9904. 2017-08-29 [PMID: 28851944] (Mouse)
• T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function J. Immunol., 2017-08-02;0(0):. 2017-08-02 [PMID: 28768723] (Mouse)
• A Imai, K Satoi, E Fujimoto, K Sato Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis Heliyon, 2017-06-22;3(6):e00327. 2017-06-22 [PMID: 28707000] (Mouse)
• S Kang, S Ahn, J Lee, JY Kim, M Choi, V Gujrati, H Kim, J Kim, EC Shin, S Jon Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses J Control Release, 2017-04-18;256(0):56-67. 2017-04-18 [PMID: 28428066] (Mouse)
• JS Bowers, MH Nelson, K Majchrzak, SR Bailey, B Rohrer, AD Kaiser, C Atkinson, L Gattinoni, CM Paulos Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion JCI Insight, 2017-03-09;2(5):e90772. 2017-03-09 [PMID: 28289713] (Mouse)
• Y Zhou, H Chen, L Liu, X Yu, GK Sukhova, M Yang, L Zhang, VC Kyttaris, GC Tsokos, IE Stillman, T Ichimura, JV Bonventre, P Libby, GP Shi CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice J. Immunol, 2017-02-20;0(0):. 2017-02-20 [PMID: 28219888] (Mouse)
• NK cells require antigen-specific memory CD4+ T cells to mediate superior effector functions during HSV-2 recall responses in vitro J. Leukoc. Biol, 2016-12-14;0(0):. 2016-12-14 [PMID: 27974365] (Mouse)
• Saeid Bouzari Comparison of potential protection conferred by three immunization strategies (protein/protein, DNA/DNA, and DNA/protein) against Brucella infection using Omp2b in BALB/c Mice Vet. Microbiol., 2016-11-05;197(0):47-52. 2016-11-05 [PMID: 27938682] (Mouse)
• J Yun, SM Gu, TH Lee, YJ Song, S Seong, YH Kim, HJ Cha, KM Han, J Shin, H Oh, K Jung, C Ahn, HK Park, HS Kim Synthetic Cannabinoid-Induced Immunosuppression Augments Cerebellar Dysfunction in Tetanus-Toxin Treated Mice Biomol Ther (Seoul), 2017-05-01;25(3):266-271. 2017-05-01 [PMID: 27871157] (Mouse)
• Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype MBio, 2016-09-20;7(5):. 2016-09-20 [PMID: 27651361] (Mouse)
• Testosterone-Mediated Endocrine Function and TH1/TH2 Cytokine Balance after Prenatal Exposure to Perfluorooctane Sulfonate: By Sex Status Int J Mol Sci, 2016-09-12;17(9):. 2016-09-12 [PMID: 27626407] (Mouse)
• Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge PLoS ONE, 2016-05-19;11(5):e0155870. 2016-05-19 [PMID: 27196728] (Mouse)
• Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis PLoS ONE, 2016-05-09;11(5):e0154630. 2016-05-09 [PMID: 27159398] (Mouse)
• Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides Integr Cancer Ther, 2016-04-29;15(4):NP13-NP25. 2016-04-29 [PMID: 27130724] (Mouse)
• Radjabova V, Mastroeni P, Skjodt K, Zaccone P, de Bono B, Goodall J, Chilvers E, Juss J, Jones D, Trowsdale J, Barrow A TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils. J Immunol, 2015-08-26;195(7):3149-59. 2015-08-26 [PMID: 26311901] (Mouse)
• Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. J Immunol, 2015-08-03;195(6):2612-23. 2015-08-03 [PMID: 26238491] (Mouse)
• Na B, Kim H, Piragyte I, Oh H, Kwon M, Akber U, Lee H, Park D, Song W, Park Z, Im S, Rho M, Hyun Y, Kim M, Jun C TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse. J Cell Biol, 2015-04-13;209(1):143-62. 2015-04-13 [PMID: 25869671] (Mouse)
• Pfarr K, Danciu C, Arlt O, Neske C, Dehelean C, Pfeilschifter J, Radeke H Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin. PLoS ONE, 2015-03-10;10(3):e0118802. 2015-03-10 [PMID: 25756279] (Mouse)
• Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N The glycosylated Rv1860 protein of mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG. PLoS Pathog, 2014-06-12;10(6):e1004176. 2014-06-12 [PMID: 24945624] (Mouse)
• Kim H, Na B, Kwon M, Ko Y, Han W, Jun C Dynamic motile T cells highly respond to the T cell stimulation via PI3K-Akt and NF-kappaB pathways. PLoS ONE, 2013-03-26;8(3):e59793. 2013-03-26 [PMID: 23555783] (Mouse)
• Yan , L, Singh , L S, Zhang , L, Xu , Y Role of OGR1 in myeloid-derived cells in prostate cancer. Oncogene, 2012-12-10;33(2):157-64. 2012-12-10 [PMID: 23222714] (Mouse)
• Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model. Eur J Immunol, 2013-01-31;43(3):655-66. 2013-01-31 [PMID: 23208786] (Mouse)
• Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect. Immun., 2011-10-24;80(1):100-9. 2011-10-24 [PMID: 22025515] (Mouse)
• Li Y, Qu P, Wu L, Li B, Du H, Yan C Api6/AIM/Sp{alpha}/CD5L Overexpression in Alveolar Type II Epithelial Cells Induces Spontaneous Lung Adenocarcinoma. Cancer Res., 2011-06-22;71(16):5488-99. 2011-06-22 [PMID: 21697282] (Mouse)
• Zhang X, Yuan Z, Duan Q, Zhu H, Yu H, Wang Q Mucosal immunity in mice induced by orally administered transgenic rice. Vaccine, 2009-01-13;27(10):1596-600. 2009-01-13 [PMID: 19146896] (Mouse)
• Han Y, Guo Q, Zhang M, Chen Z, Cao X CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J. Immunol., 2009-01-01;182(1):111-20. 2009-01-01 [PMID: 19109141] (Mouse)
• Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. Circulation, 2008-10-27;118(20):2063-72. 2008-10-27 [PMID: 18955666] (Mouse)
• Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G, Hildeman DA, Belkaid Y, Chougnet C Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J. Immunol., 2008-08-01;181(3):1835-48. 2008-08-01 [PMID: 18641321] (Mouse)
• Csoka B, Himer L, Selmeczy Z, Vizi ES, Pacher P, Ledent C, Deitch EA, Spolarics Z, Nemeth ZH, Hasko G Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function. FASEB J., 2008-07-14;22(10):3491-9. 2008-07-14 [PMID: 18625677] (Mouse)
• Florindo HF, Pandit S, Goncalves LM, Alpar HO, Almeida AJ Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses. Vaccine, 2008-06-17;26(33):4168-77. 2008-06-17 [PMID: 18599166] (Mouse)
• Miyazaki Y, Shimanoe Y, Wang S, Yoshida H Amelioration of delayed-type hypersensitivity responses by IL-27 administration. Biochem. Biophys. Res. Commun., 2008-06-20;373(3):397-402. 2008-06-20 [PMID: 18572017] (Mouse)
• Ishikawa H, Tanaka K, Maeda Y, Aiba Y, Hata A, Tsuji NM, Koga Y, Matsumoto T Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells. Clin. Exp. Immunol., 2008-05-05;153(1):127-35. 2008-05-05 [PMID: 18460018] (Mouse)
• Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation. Neurobiol. Dis., 2007-10-16;29(2):336-53. 2007-10-16 [PMID: 18055209] (Mouse)
• Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol., 2007-11-11;8(12):1372-9. 2007-11-11 [PMID: 17994023] (Mouse)
• Wang KX, Shi Y, Denhardt DT Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production. Proc. Natl. Acad. Sci. U.S.A., 2007-09-04;104(37):14777-82. 2007-09-04 [PMID: 17785423] (Mouse)
• Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis. Vaccine, 2007-07-27;25(37):6730-43. 2007-07-27 [PMID: 17698261] (Mouse)
• Hernandez Sanabria MX, Afonso LC, Golgher D, Tafuri WL, Vieira LQ CD8+ T cells are not required for vaccine-induced immunity against Leishmania amazonensis in IL-12/23P40(-/-) C57BL/6 mice. Microbes Infect., 2007-05-18;9(9):1124-34. 2007-05-18 [PMID: 17662634] (Mouse)
• Perchonock CE, Pajerowski AG, Nguyen C, Shapiro MJ, Shapiro VS The related adaptors, adaptor in lymphocytes of unknown function X and Rlk/Itk-binding protein, have nonredundant functions in lymphocytes. J. Immunol., 2007-08-01;179(3):1768-75. 2007-08-01 [PMID: 17641043] (Mouse)
• Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity, 2007-04-12;26(4):445-59. 2007-04-12 [PMID: 17433730] (Mouse)
• Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells. Clin. Exp. Immunol., 2007-03-01;147(3):540-6. 2007-03-01 [PMID: 17302905] (Mouse)
• Moore F, Buonocore S, Aksoy E, Ouled-Haddou N, Goriely S, Lazarova E, Paulart F, Heirman C, Vaeremans E, Thielemans K, Goldman M, Flamand V An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha. J. Immunol., 2007-02-01;178(3):1301-11. 2007-02-01 [PMID: 17237376] (Mouse)
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FAQs for IL-2 (DY402). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Il2