Mouse IL-13 Culture Media Quantikine ELISA, 2 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse IL-13 Culture Media Quantikine ELISA, 2 Plate Summary

Background
The Quantikine Mouse IL-13 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-13 levels in cell culture supernates. It contains E. coli-expressed recombinant mouse IL-13 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse IL-13 accurately. Results obtained using natural mouse IL-13 showed dos...e curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-13.
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Specificity
Natural and recombinant mouse IL-13
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il13

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
M1300CB in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-13 Culture Media Quantikine ELISA, 2 Plate

  • ALRHMGC116789
  • BHR1interleukin-13
  • IL13
  • IL-13
  • IL-13MGC116788
  • interleukin 13
  • MGC116786
  • NC30
  • P600

Background

IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for IL-13 (M1300CB)(117)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
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Filter By Species
Human
(1)
Mouse
(116)
All Species
Showing Publications 1 - 10 of 117. Show All 117 Publications.
Publications using M1300CB Applications Species
W Wei, W Chen, N He HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation Journal of Translational Medicine, 2021;19(1):258. 2021 [PMID: 34118928] (Mouse) Mouse
Á Rol, T Todorovski, P Martin-Mal, A Escolà, E Gonzalez-R, E Aragón, X Verdaguer, M Vallès-Mir, J Farrera-Si, E Puig, J Fernández-, B Ponsati, M Delgado, A Riera, MJ Macias Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease Nature Communications, 2021;12(1):1869. 2021 [PMID: 33767180] (Mouse) Mouse
E Saba, YY Lee, MH Rhee, SD Kim Alleviation of Ulcerative Colitis Potentially through th1/th2 Cytokine Balance by a Mixture of Rg3-enriched Korean Red Ginseng Extract and Persicaria tinctoria Molecules, 2020;25(22):. 2020 [PMID: 33182623] (Mouse) Mouse
W Zhou, J Zhang, S Toki, K Goleniewsk, AE Norlander, DC Newcomb, P Wu, KL Boyd, H Kita, RS Peebles COX Inhibition Increases Alternaria-Induced Pulmonary Group 2 Innate Lymphoid Cell Responses and IL-33 Release in Mice J. Immunol., 2020;0(0):. 2020 [PMID: 32690653] (Mouse) Mouse
RR E-Lacerda, CJ Teixeira, S Bordin, E Antunes, GF Anhê Maternal Obesity in Mice Exacerbates the Allergic Inflammatory Response in the Airways of Male Offspring Nutrients, 2019;11(12):. 2019 [PMID: 31805682] (Mouse) Mouse
W Hu, L Ma, G Yang, X Zeng, J Liu, B Cheng, T Hu, H Zhao, Z Liu Der p2?A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis Mol Med Rep, 2019;0(0):. 2019 [PMID: 31638224] (Mouse) Mouse
CT Wu, FH Lin, YT Lee, MS Ku, KH Lue Effect of Lactobacillus rhamnosus GG immunopathologic changes in chronic mouse asthma model J Microbiol Immunol Infect, 2019;0(0):. 2019 [PMID: 30952512] (Mouse) Mouse
I Sulaiman, K Tan, N Mohtarrudi, JC Woei Lim, J Stanslas Andrographolide prevented toluene diisocyanate-induced occupational asthma and aberrant airway E-cadherin distribution via p38 MAPK-dependent Nrf2 induction Pulm Pharmacol Ther, 2018;0(0):. 2018 [PMID: 30244166] (Mouse) Mouse
S Carvalho, M Ferrini, L Herritt, A Holian, Z Jaffar, K Roberts Multi-Walled Carbon Nanotubes Augment Allergic Airway Eosinophilic Inflammation by Promoting Cysteinyl Leukotriene Production Front Pharmacol, 2018;9(0):585. 2018 [PMID: 29922162] (Mouse) Mouse
MH Yi, HP Kim, KY Jeong, JY Kim, IY Lee, TS Yong Effects of the Th2-dominant milieu on allergic responses in Der f 1-activated mouse basophils and mast cells Sci Rep, 2018;8(1):7706. 2018 [PMID: 29769546] (Mouse) Mouse
Show All 117 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IL-13 (M1300CB). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP M1300CB
HRP M1300CB
HRP M1300CB

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Bioinformatics Tool for IL-13 (M1300CB)

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Blogs on IL-13.

Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

FLICE, FLICE, baby
Cell death via apoptosis is a fundamental cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. All caspases exist in a precursor form compose...  Read full blog post.

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Bioinformatics

Gene Symbol Il13