Mouse Gas6 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse Gas6 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Gas6

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY986.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Gas6 DuoSet ELISA, 15 Plate

  • AXLLG
  • AXLLGAXL stimulatory factor
  • AXSFAXL receptor tyrosine kinase ligand
  • DKFZp666G247
  • FLJ34709
  • Gas6
  • GAS-6
  • growth arrest-specific 6
  • growth arrest-specific protein 6

Background

Gas6 (Growth Arrest Specific 6) is a secreted protein that contains an extensively gamma-carboxylated N-terminal Gla domain and is dependent upon vitamin K for activity. Gas6 signals through the receptors Axl, Dtk/Tyro3, and Mer and is inhibited by shed soluble forms of Axl and Mer. Gas6 protects cells from stress-induced apoptosis and promotes phagocytosis of apoptotic cell debris, promotes platelet activation but inhibits inflammatory cytokine production, and inhibits VEGF-induced angiogenesis, and regulates tumor cell invasiveness.

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Publications for Gas6 (DY986)(9)

We have publications tested in 1 confirmed species: Mouse.


Filter By Application
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Filter By Species
Mouse
(9)
All Species
Showing Publications 1 - 9 of 9.
Publications using DY986 Applications Species
PY Dumas, C Naudin, S Martin-Lan, B Izac, L Casetti, O Mansier, B Rousseau, A Artus, M Dufossée, A Giese, P Dubus, A Pigneux, V Praloran, A Bidet, A Villacrece, AV Guitart, N Milpied, O Kosmider, I Vigon, V Desplat, I Dusanter-F, JM Pasquet Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL Haematologica, 2019;0(0):. 2019 [PMID: 30923103] (Mouse) Mouse
Y Chen, J Wang, X Chen, D Li, X Han Microcystin-leucine arginine mediates apoptosis and engulfment of Leydig cell by testicular macrophages resulting in reduced serum testosterone levels Aquat. Toxicol., 2018;199(0):116-126. 2018 [PMID: 29621671] (Mouse) Mouse
A Decker, Y Jung, FC Cackowski, K Yumoto, J Wang, RS Taichman Sympathetic signaling reactivates quiescent�disseminated prostate cancer cells in the bone marrow Mol. Cancer Res., 2017;0(0):. 2017 [PMID: 28814453] (Mouse) Mouse
M Kurowska-S, S Alivernini, EG Melchor, A Elmesmari, B Tolusso, C Tange, L Petricca, DS Gilchrist, G Di Sante, C Keijzer, L Stewart, C Di Mario, V Morrison, JM Brewer, D Porter, S Milling, RD Baxter, D McCarey, E Gremese, G Lemke, G Ferracciol, C McSharry, IB McInnes MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis Nat Commun, 2017;8(0):15877. 2017 [PMID: 28639625] (Mouse) Mouse
Axl is required for TGF-?2-induced dormancy of prostate cancer cells in the bone marrow Sci Rep, 2016;6(0):36520. 2016 [PMID: 27819283] (Mouse) Mouse
Zagorska A, Traves P, Lew E, Dransfield I, Lemke G Diversification of TAM receptor tyrosine kinase function. Nat Immunol, 2014;15(10):920-8. 2014 [PMID: 25194421] (Mouse) Mouse
Deng T, Zhang Y, Chen Q, Yan K, Han D Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages. Immunology, 2012;135(1):40-50. 2012 [PMID: 22043818] (Mouse) Mouse
Anwar A, Keating AK, Joung D, Sather S, Kim GK, Sawczyn KK, Brandao L, Henson PM, Graham DK Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress. J. Leukoc. Biol., 2009;86(1):73-9. 2009 [PMID: 19386698] (Mouse) Mouse
Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. Blood, 2007;111(8):4096-105. 2007 [PMID: 18156494] (Mouse) Mouse

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Product General Protocols

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FAQs for Gas6 (DY986). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
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Bioinformatics

Gene Symbol Gas6