Mouse CCL25/TECK DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL25/TECK DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl25

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL25/TECK DuoSet ELISA, 15 Plate

• C-C motif chemokine 25
• CCL25
• chemokine (C-C motif) ligand 25
• Chemokine TECK
• Ck beta-15
• Ckb15
• SCYA25TECKvar
• small inducible cytokine subfamily A (Cys-Cys), member 25
• Small-inducible cytokine A25
• TECK
• TECKMGC150327
• thymus expressed chemokine
• Thymus-expressed chemokine

Background

CCL25/TECK is a CC chemokine is produced by stromal cells in the thymus and epithelial cells of the small intestine, particularly the jejunum and ileum. It binds to and induces chemoattraction through CCR9 on immature pre-T cells and thymocytes. CCL25 induces the homing of several lymphocyte populations to the small intestine, including Integrin a4b7+ gamma/delta T cells, Integrin aEb7+ CD8+ T cells, and IgA-producing plasma cells. In cancer, CCL25 promotes the metastasis of melanoma cells to the small intestine, the migration and invasion of some breast carcinomas, and the attraction of mesenchymal stromal cells to multiple myelomas. CCL25 attracts CCR9+ monocytes and macrophages in rheumatoid arthritis and CCR9+ macrophages in atherosclerosis.

Publications for CCL25/TECK (DY481)(3)

Publications using DY481

• Bao, K;Gu, X;Song, Y;Zhou, Y;Chen, Y;Yu, X;Yuan, W;Shi, L;Zheng, J;Hong, M; TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma Nature communications 2024-09-08 [PMID: 39245681] (Mouse)
• Lucas B, White A, Ulvmar M, Nibbs R, Sitnik K, Agace W, Jenkinson W, Anderson G, Rot A CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice. Eur J Immunol, 2015-01-16;45(2):574-83. 2015-01-16 [PMID: 25521433] (Mouse)
• Miething , Corneliu, Scuoppo , Claudio, Bosbach , Benedikt, Appelmann , Iris, Nakitandwe , Joy, Ma , Jing, Wu , Gang, Lintault , Laura, Auer , Martina, Premsrirut , Prem K, Teruya-Feldstein , Julie, Hicks , James, Benveniste , Helene, Speicher , Michael, Downing , James R, Lowe , Scott W PTEN action in leukaemia dictated by the tissue microenvironment. Nature, 2014-05-04;510(7505):402-6. 2014-05-04 [PMID: 24805236] (Mouse)

Bioinformatics

• Gene Symbol: Ccl25