Mouse CCL25/TECK DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL25/TECK DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl25

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL25/TECK DuoSet ELISA, 15 Plate

• C-C motif chemokine 25
• CCL25
• chemokine (C-C motif) ligand 25
• Chemokine TECK
• Ck beta-15
• Ckb15
• SCYA25TECKvar
• small inducible cytokine subfamily A (Cys-Cys), member 25
• Small-inducible cytokine A25
• TECK
• TECKMGC150327
• thymus expressed chemokine
• Thymus-expressed chemokine

Background

CCL25/TECK is a CC chemokine is produced by stromal cells in the thymus and epithelial cells of the small intestine, particularly the jejunum and ileum. It binds to and induces chemoattraction through CCR9 on immature pre-T cells and thymocytes. CCL25 induces the homing of several lymphocyte populations to the small intestine, including Integrin a4b7+ gamma/delta T cells, Integrin aEb7+ CD8+ T cells, and IgA-producing plasma cells. In cancer, CCL25 promotes the metastasis of melanoma cells to the small intestine, the migration and invasion of some breast carcinomas, and the attraction of mesenchymal stromal cells to multiple myelomas. CCL25 attracts CCR9+ monocytes and macrophages in rheumatoid arthritis and CCR9+ macrophages in atherosclerosis.

Publications for CCL25/TECK (DY481)(4)

Publications using DY481

• Bao, K;Gu, X;Song, Y;Zhou, Y;Chen, Y;Yu, X;Yuan, W;Shi, L;Zheng, J;Hong, M; TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma Nature communications 2024-09-08 [PMID: 39245681] (Mouse)
• Marine Fidelle # 1 2 3, Conrad Rauber # 1 2 3 4, Carolina Alves Costa Silva # 1 2 3, Ai-Ling Tian 1 2 5 6, Imran Lahmar 1 2 3, Anne-Laure Mallard de La Varende 1 2 3, Liwei Zhao 1 5 6, Cassandra Thelemaque 1 3, Isabelle Lebhar 1 3, Meriem Messaoudene 7, Eugenie Pizzato 1 3, Roxanne Birebent 1 2 3, Maxime Descartes Mbogning Fonkou 1 3, Silvia Zoppi 1 2 8, Anna Reni 1 2 9, Cécile Dalban 10, Marion Leduc 1 5 6, Gladys Ferrere 1 3 11, Sylvère Durand 1 5 6, Pierre Ly 1 3 12, Aymeric Silvin 1 3, Kevin Mulder 1 2 3, Charles-Antoine Dutertre 1 3, Florent Ginhoux 1 3, Satoru Yonekura 1 2 3, Maria Paula Roberti 1 3 13 14, Maryam Tidjani-Alou 1 3, Safae Terrisse 1 2 3, Jianzhou Chen 1 3, Oliver Kepp 1 5 6, Angela Schippers 15, Norbert Wagner 15, Javier Suárez-Gosálvez 16, Sebastian Kobold 16 17, Jean-Eudes Fahrner 1 2 3, Corentin Richard 7, Jacques Bosq 18, Leonardo Lordello 1 3, Giacomo Vitali 19, Nathalie Galleron 19, Benoît Quinquis 19, Emmanuelle Le Chatelier 19, Lucas Blanchard 20, Jean-Philippe Girard 20, Anne Jarry 21, Nadine Gervois 21, Emmanuelle Godefroy 21, Nathalie Labarrière 21 22, Ronald Koschny 4, Romain Daillère 11, Benjamin Besse 1 2, Caroline Truntzer 23, François Ghiringhelli 23, Nicolas Coatnoan 24 25, Vanessa Mhanna 24 25, David Klatzmann 24 25, Damien Drubay 1 26 27, Laurence Albiges 1 2, Andrew Maltez Thomas 28, Nicola Segata 28 29, François-Xavier Danlos 1 2 3 12 30, Aurélien Marabelle 1 2 3 12 30, Bertrand Routy 7 31, Lisa Derosa # 1 2 3 12, Guido Kroemer # 5 6 32, Laurence Zitvogel # 1 2 3 12 A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers Science 2023-06-09 [PMID: 37289890] (Mouse)
• Lucas B, White A, Ulvmar M, Nibbs R, Sitnik K, Agace W, Jenkinson W, Anderson G, Rot A CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice. Eur J Immunol, 2015-01-16;45(2):574-83. 2015-01-16 [PMID: 25521433] (Mouse)
• Miething , Corneliu, Scuoppo , Claudio, Bosbach , Benedikt, Appelmann , Iris, Nakitandwe , Joy, Ma , Jing, Wu , Gang, Lintault , Laura, Auer , Martina, Premsrirut , Prem K, Teruya-Feldstein , Julie, Hicks , James, Benveniste , Helene, Speicher , Michael, Downing , James R, Lowe , Scott W PTEN action in leukaemia dictated by the tissue microenvironment. Nature, 2014-05-04;510(7505):402-6. 2014-05-04 [PMID: 24805236] (Mouse)

FAQs for CCL25/TECK (DY481). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Ccl25