Mouse C-Reactive Protein/CRP Quantikine ELISA Kit



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Reactivity MuSpecies Glossary
Applications ELISA

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Mouse C-Reactive Protein/CRP Quantikine ELISA Kit Summary

The Quantikine Mouse C-Reactive Protein/CRP immunoassay is a 4.5 hour solid-phase ELISA designed to measure CRP in mouse cell culture supernates, tissue lysates, serum, and plasma. It contains NS0-expressed recombinant mouse CRP and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant mouse CRP. Results obtained using natu...ral mouse CRP showed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse CRP.
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Natural and recombinant mouse CRP.
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using MCRP00.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse C-Reactive Protein/CRP Quantikine ELISA Kit

  • C-Reactive Protein
  • C-reactive protein, pentraxin-related
  • CRP
  • MGC88244
  • pentraxin 1
  • PTX1MGC149895


C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for C-Reactive Protein/CRP (MCRP00)(13)

We have publications tested in 1 confirmed species: Mouse.

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Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using MCRP00 Applications Species
E Palathinga, J George, M Tarique, S Iyer, P Sahay, B Gomez Agui, DB Edwards, B Giri, V Sethi, T Jain, P Sharma, U Vaish, HK C Jacob, A Ferrantell, CL Maynard, AK Saluja, RK Dawra, V Dudeja Pirfenidone increases IL10 and improves acute pancreatitis in multiple clinically relevant murine models JCI Insight, 2021;0(0):. 2021 [PMID: 34847076] (Mouse) Mouse
Z Zhang, H Na, Q Gan, Q Tao, Y Alekseyev, J Hu, Z Yan, JB Yang, H Tian, S Zhu, Q Li, IM Rajab, JK Blusztajn, B Wolozin, A Emili, X Zhang, T Stein, LA Potempa, WQ Qiu Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease? Aging Cell, 2021;0(0):e13501. 2021 [PMID: 34687487] (Mouse) Mouse
K Claesen, L Roth, JC Mertens, K Hermans, Y Sim, D Hendriks Pleiotropic Effects of Atorvastatin Result in a Downregulation of the Carboxypeptidase U System (CPU, TAFIa, CPB2) in a Mouse Model of Advanced Atherosclerosis Pharmaceutics, 2021;13(10):. 2021 [PMID: 34684024] (Mouse) Mouse
X Liu, Y Xiao, Q Zhu, Y Cui, H Hao, M Wang, PJ Cowan, RJ Korthuis, G Li, Q Sun, Z Liu Circulating Endothelial Progenitor Cells Are Preserved in Female Mice Exposed to Ambient Fine Particulate Matter Independent of Estrogen International Journal of Molecular Sciences, 2021;22(13):. 2021 [PMID: 34281260] (Mouse) Mouse
JK Nam, AR Kim, SH Choi, JH Kim, KJ Choi, S Cho, JW Lee, HJ Cho, YW Kwon, J Cho, KS Kim, J Kim, HJ Lee, TS Lee, S Bae, HJ Hong, YJ Lee An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage Nature Communications, 2021;12(1):3279. 2021 [PMID: 34078883] (Mouse) Mouse
T Yasuda, M Koiwa, A Yonemura, K Miyake, R Kariya, S Kubota, T Yokomizo-N, N Yasuda-Yos, T Uchihara, R Itoyama, L Bu, L Fu, K Arima, D Izumi, S Iwagami, K Eto, M Iwatsuki, Y Baba, N Yoshida, H Ohguchi, S Okada, K Matsusaki, G Sashida, A Takahashi, P Tan, H Baba, T Ishimoto Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination Cell Reports, 2021;34(8):108779. 2021 [PMID: 33626356] (Mouse) Mouse
Y Yoon, G Kim, MG Noh, JH Park, M Jang, S Fang, H Park Lactobacillus fermentum promotes adipose tissue oxidative phosphorylation to protect against diet-induced obesity Exp. Mol. Med., 2020;0(0):. 2020 [PMID: 32917958] (Mouse) Mouse
J Varghese, JV James, R Anand, M Narayanasa, G Rebekah, B Ramakrishn, AJ Nellickal, M Jacob Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet J. Nutr. Biochem., 2020;84(0):108441. 2020 [PMID: 32629238] (Mouse) Mouse
S Yeo, H Park, E Seo, J Kim, BK Kim, IS Choi, CS Huh Anti-Inflammatory and Gut Microbiota Modulatory Effect of Lactobacillus rhamnosus Strain LDTM 7511 in a Dextran Sulfate Sodium-Induced Colitis Murine Model Microorganisms, 2020;8(6):. 2020 [PMID: 32512895] (Mouse) Mouse
NO McPherson, M Lane Metformin treatment of high-fat diet-fed obese male mice restores sperm function and fetal growth, without requiring weight loss Asian J. Androl., 2020;0(0):. 2020 [PMID: 32098932] (Mouse) Mouse
Show All 13 Publications.

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Gene Symbol Crp