Mouse C-Reactive Protein/CRP Quantikine ELISA Kit

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Mouse C-Reactive Protein/CRP Quantikine ELISA Kit Summary

Background
The Quantikine Mouse C-Reactive Protein/CRP immunoassay is a 4.5 hour solid-phase ELISA designed to measure CRP in mouse cell culture supernates, tissue lysates, serum, and plasma. It contains NS0-expressed recombinant mouse CRP and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant mouse CRP. Results obtained using natu...ral mouse CRP showed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse CRP.
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Specificity
Natural and recombinant mouse CRP.
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Crp

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MCRP00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse C-Reactive Protein/CRP Quantikine ELISA Kit

  • C-Reactive Protein
  • C-reactive protein, pentraxin-related
  • CRP
  • MGC88244
  • pentraxin 1
  • PTX1MGC149895

Background

C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for C-Reactive Protein/CRP (MCRP00)(5)

We have publications tested in 1 confirmed species: Mouse.


Filter By Application
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Mouse
(5)
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Showing Publications 1 - 5 of 5.
Publications using MCRP00 Applications Species
J Varghese, JV James, R Anand, M Narayanasa, G Rebekah, B Ramakrishn, AJ Nellickal, M Jacob Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet J. Nutr. Biochem., 2020;84(0):108441. 2020 [PMID: 32629238] (Mouse) Mouse
NO McPherson, M Lane Metformin treatment of high-fat diet-fed obese male mice restores sperm function and fetal growth, without requiring weight loss Asian J. Androl., 2020;0(0):. 2020 [PMID: 32098932] (Mouse) Mouse
C Liang, J Li, C Lu, D Xie, J Liu, C Zhong, X Wu, R Dai, H Zhang, D Guan, B Guo, B He, F Li, X He, W Zhang, BT Zhang, G Zhang, A Lu HIF1alpha inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis Nat Commun, 2019;10(1):4579. 2019 [PMID: 31594926] (Mouse) Mouse
DK Lee, JH Kim, J Kim, S Choi, M Park, W Park, S Kim, KS Lee, T Kim, J Jung, YK Choi, KS Ha, MH Won, TR Billiar, YG Kwon, YM Kim REDD-1 aggravates endotoxin-induced inflammation via atypical NF-?B activation FASEB J., 2018;0(0):fj201701436R. 2018 [PMID: 29547704] (Mouse) Mouse
L Wang, H Ma, Y Xue, H Shi, T Ma, X Cui Berberine inhibits the ischemia-reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3-kinase/RAC-? serine/threonine-protein kinase and nuclear factor-?B signaling pathways Exp Ther Med, 2018;15(2):1225-1232. 2018 [PMID: 29403554] (Mouse) Mouse

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Product General Protocols

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FAQs for C-Reactive Protein/CRP (MCRP00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP MCRP00

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Bioinformatics

Gene Symbol Crp