MOG Antibody

Immunohistochemistry-Paraffin: MOG Antibody [NBP1-87458] - Staining of human pancreas shows no positivity as expected.

Immunohistochemistry-Paraffin: MOG Antibody [NBP1-87458] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in subsets of glial cells.

Immunohistochemistry-Paraffin: MOG Antibody [NBP1-87458] - Staining of human cerebral cortex shows moderate membranous positivity in glial cells.

Immunohistochemistry-Paraffin: MOG Antibody [NBP1-87458] - Staining of human cerebellum shows moderate membranous positivity in cells in granular layer.

Immunohistochemistry-Paraffin: MOG Antibody [NBP1-87458] - Staining of human fallopian tube shows no positivity as expected.

Product Discontinued

MOG Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: ALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWVSPG
• Marker: Oligodendrocyte Marker
• Predicted Species: Mouse (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MOG
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  MOG Recombinant Protein Antigen (NBP1-87458PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for MOG Antibody

• MGC26137
• MOG Ig-AluB
• MOG
• MOGIG2
• myelin oligodendrocyte glycoprotein
• myelin-oligodendrocyte glycoprotein

Background

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MOG