Mkl1 Antibody (OTI3G7) [Allophycocyanin]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI3G7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Mkl1 Antibody (OTI3G7) [Allophycocyanin] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 165-397 of human MKL1(NP_065882) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MRTFA
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Mkl1 Antibody (OTI3G7) [Allophycocyanin]

• AMKL
• KIAA1438
• MALSAP and coiled-coil domain
• megakaryoblastic leukemia (translocation) 1
• Megakaryoblastic leukemia 1 protein
• Megakaryocytic acute leukemia protein
• MKL/myocardin-like protein 1
• Myocardin-related transcription factor A
• RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein

Background

MKL1 (megakaryoblastic leukemia 1 protein) was identified as part of a t(1;22) translocation with RBM15 associated with acute megakaryoblastic leukemia. It is a transcriptional coactivator of serum response factor (SRF) that promotes muscle differentiation and also plays a role in promoting maturation of megakaryocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MRTFA