MHC Class II Antibody (NIMR-4) [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IHC, ICC/IF
Clone
NIMR-4
Clonality
Monoclonal
Host
Rat
Conjugate
Biotin
Concentration
0.5 mg/ml

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MHC Class II Antibody (NIMR-4) [Biotin] Summary

Immunogen
The immunogen is a peptide made to the amino acid region MHC Class II
Specificity
MHC Class II molecules
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Rat
Gene
HLA-DMA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1 ug/10^6 cells
  • Immunocytochemistry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen 1:10-1:500
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for MHC Class II Antibody (NIMR-4) [Biotin]

  • class II histocompatibility antigen, M alpha chain
  • D6S222E
  • DMA
  • HLA class II histocompatibility antigen, DM alpha chain
  • major histocompatibility complex, class II, DM alpha
  • MHC class II antigen DMA
  • Really interesting new gene 6 protein
  • RING6HLADM

Background

The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional MHC Class II Products

Array NBP1-28160

Research Areas for MHC Class II Antibody (NBP1-28160)

Find related products by research area.

Blogs on MHC Class II.

Immune Cell Metabolic Flux Influences Type I Diabetes
By Hunter MartinezWhat is Immunometabolism?It is well established that abnormal metabolic environments can be a risk factor for disease development. One characteristic example is the role of dyslipidemia (high lev...  Read full blog post.


  Read full blog post.

CD74 - a central player in antigen presentation by MHC class II
Cluster of differentiation 74 (CD74) is an important integral membrane protein that serves as a chaperone for MHC class II molecules. CD74, also known as the invariant chain or Ii, is needed for the proper folding and trafficking of MHC class II in...  Read full blog post.

Lymphocyte activation gene 3 (LAG3): No lag time in immune response
The LAG3 protein belongs to the Ig superfamily and contains 4 extracellular Ig-like domains (D1-D4). This molecule plays an key role in the immune response through negative regulation of T-cell proliferation, function, and homeostasis. It is required ...  Read full blog post.

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Bioinformatics

Gene Symbol HLA-DMA