MHC Class II Antibody (NIMR-4) - Azide and BSA Free

Images

 
Flow Cytometry: MHC Class II Antibody (NIMR-4) [NBP1-28158] - BALB/c mouse splenocytes were stained with Rat Anti-Mouse MHC Class II-UNLB followed by Mouse Anti-Rat IgG2b-AF488.
Flow Cytometry: MHC Class II Antibody (NIMR-4) [NBP1-28158] - Analysis using the Biotin conjugate of NBP1-28158. Multiple staining of BALB/c splenocytes.
Flow Cytometry: MHC Class II Antibody (NIMR-4) [NBP1-28158] - Analysis using the FITC conjugate of NBP1-28158. Staining of less or equal to ug/10^6 BALB/c spleen cells with Rat Anti-Mouse MHC II-FITC, following which ...read more
Flow Cytometry: MHC Class II Antibody (NIMR-4) [NBP1-28158] - Analysis using the PE conjugate of NBP1-28158. Multiple staining of BALB/c splenocytes.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
NIMR-4
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
0.5 mg/ml

Order Details

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Catalog# & Conjugate Size Price

MHC Class II Antibody (NIMR-4) - Azide and BSA Free Summary

Immunogen
The immunogen is a peptide made to the amino acid region MHC Class II
Specificity
MHC Class II molecules
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Rat
Gene
HLA-DMA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1 ug/10^6 cells
Publications
Read Publication using
NBP1-28158 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for MHC Class II Antibody (NIMR-4) - Azide and BSA Free

  • class II histocompatibility antigen, M alpha chain
  • D6S222E
  • DMA
  • HLA class II histocompatibility antigen, DM alpha chain
  • major histocompatibility complex, class II, DM alpha
  • MHC class II antigen DMA
  • Really interesting new gene 6 protein
  • RING6HLADM

Background

The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MHC Class II Antibody (NBP1-28158)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: FLOW.


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FLOW
(1)
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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional MHC Class II Products

Array NBP1-28158

Research Areas for MHC Class II Antibody (NBP1-28158)

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Blogs on MHC Class II.

Immune Cell Metabolic Flux Influences Type I Diabetes
By Hunter MartinezWhat is Immunometabolism?It is well established that abnormal metabolic environments can be a risk factor for disease development. One characteristic example is the role of dyslipidemia (high lev...  Read full blog post.


  Read full blog post.

CD74 - a central player in antigen presentation by MHC class II
Cluster of differentiation 74 (CD74) is an important integral membrane protein that serves as a chaperone for MHC class II molecules. CD74, also known as the invariant chain or Ii, is needed for the proper folding and trafficking of MHC class II in...  Read full blog post.

Lymphocyte activation gene 3 (LAG3): No lag time in immune response
The LAG3 protein belongs to the Ig superfamily and contains 4 extracellular Ig-like domains (D1-D4). This molecule plays an key role in the immune response through negative regulation of T-cell proliferation, function, and homeostasis. It is required ...  Read full blog post.

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Bioinformatics

Gene Symbol HLA-DMA