MESDC2 Antibody (513802) [Alexa Fluor™ Plus 405]

• Clone: 513802
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

MESDC2 Antibody (513802) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human MESDC2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse MESDC2 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Mesoderm development candidate gene 2 (MESDC2), also known as Boca in drosophila, is a 22 kDa protein that is required for formation of the primitive streak and mesoderm during embryogenesis. MESDC2 binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Within aa 34‑234, human MESDC2 shares 87% aa sequence identity with mouse and rat MESDC2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.