Melanocortin-4 R Antibody

Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody [NLS1032] - Analysis of anti-MC4 Receptor antibody with human brain at 4 ug/ml.

Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody [NLS1032] - Analysis of anti-MC4 Receptor antibody with transfection control at 4 ug/ ml.

Product Discontinued

Melanocortin-4 R Antibody Summary

• Immunogen: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Melanocortin-4 R.
• Localization: Cell Membrane (Multi-pass membrane protein).
• Specificity: Human MC4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Orangutan (100%), Guinea Pig (94%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MC4R
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry 7.5 - 10 ug/ml
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4-8 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Baboon (100%), Marmoset (100%), Tamarin (100%), Mouse (88%), Rat (88%), Porcine (88%), Bat (82%), Canine (82%), Hamster (82%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Melanocortin-4 R Antibody

• Fatboy
• Glu3
• MC4R
• MC4-R
• melanocortin 4 receptor
• melanocortin receptor 4
• Melanocortin-4 R
• Melanocortin4R
• Melanocortin-4R
• MGC126851
• MGC138197

Background

Melanocortin 4 receptor (MC4R), a Melanocortin Receptor, has been shown to affect food intake and energy balance. Recently MC4R has been shown to modulate erectile function and sexual behavior (Van Der Ploeg et al. 2002). Expression of MC4R has been reported in brain. Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MC4R
• Entrez:
  • 4160(Human)