Melanocortin-4 R Antibody

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Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody [NLS1032] - Analysis of anti-MC4 Receptor antibody with human brain at 4 ug/ml.
Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody [NLS1032] - Analysis of anti-MC4 Receptor antibody with transfection control at 4 ug/ ml.

Product Details

Summary
Reactivity Hu, Eq, Mk, Pm, GPSpecies Glossary
Applications IHC-P, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Melanocortin-4 R Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human MC4 Receptor.
Localization
Cell Membrane (Multi-pass membrane protein).
Specificity
Human MC4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Guinea Pig (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MC4R
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 4-21 ug/ml
  • Immunocytochemistry 7.5 - 10 ug/ml

Reactivity Notes

Chimpanzee (100%), Gorilla (100%), Orangutan (100%), Gibbon (100%), Baboon (100%), Marmoset (100%), Tamarin (100%). Predicted cross-reactivity based on sequence identity: Panda (94%), Mouse (88%), Rat (88%), Elephant (88%), Porcine (88%), Bat (82%), Canine (82%), Hamster (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Melanocortin-4 R Antibody

  • Fatboy
  • Glu3
  • MC4R
  • MC4-R
  • melanocortin 4 receptor
  • melanocortin receptor 4
  • Melanocortin-4 R
  • Melanocortin4R
  • Melanocortin-4R
  • MGC126851
  • MGC138197

Background

Melanocortin 4 receptor (MC4R), a Melanocortin Receptor, has been shown to affect food intake and energy balance. Recently MC4R has been shown to modulate erectile function and sexual behavior (Van Der Ploeg et al. 2002). Expression of MC4R has been reported in brain. Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MC4R
Entrez