Melanocortin-3 R/MC3R Antibody (345404) [Unconjugated]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
345404
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Melanocortin-3 R/MC3R Antibody (345404) [Unconjugated] Summary

Immunogen
Y3 rat myeloid cell line transfeced with mouse Melanocortin 3R/MC3R
Specificity
Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
MC3R
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells
  • CyTOF-ready

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Melanocortin-3 R/MC3R Antibody (345404) [Unconjugated]

  • BMIQ9
  • MC3
  • MC3R
  • MC3-R
  • melanocortin 3 receptor
  • melanocortin receptor 3
  • Melanocortin-3 R
  • Melanocortin3R
  • Melanocortin-3R
  • OB20
  • Obesity quantitative trait locus
  • OQTL

Background

Mouse Melanocortin 3R (MC3R) is a member of the melanocortin receptor family. The 323 amino acid G-protein-coupled 7-transmembrane glycoprotein is expressed in the brain where, along with MC4R, it binds alpha, beta and gamma melanocyte stimulating hormones and is involved in regulating energy balance. MC3R is also expressed by macrophages and plays an anti-inflammatory role in the heart and other tissues. Of the 69 aa that are extracellular, mouse MC3R shares 91% and 78% sequence identity with rat and human MC3R, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Melanocortin-3 R/MC3R Antibody (MAB3737) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB3737U
Alexa Fluor 405 FAB3737V
Alexa Fluor 488 FAB3737G
Alexa Fluor 594 FAB3737T
Alexa Fluor 647 FAB3737R
Alexa Fluor 700 FAB3737N
Alexa Fluor 750 FAB3737S

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Bioinformatics

Gene Symbol MC3R