Recombinant Human mediator of cell motility 1 His Protein

SDS-Page: Recombinant Human mediator of cell motility 1 Protein [NBP1-98912] - 15% SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human mediator of cell motility 1 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-297 of Human mediator of cell motility 1
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMMSNRV VCREASHAGS WYTASGPQLN AQLEGWLSQV QSTKRPARAI IAPHAGYTYC GSCAAHAYKQ VDPSITRRIF ILGPSHHVPL SRCALSSVDI YRTPLYDLRI DQKIYGELWK TGMFERMSLQ TDEDEHSIEM HLPYTAKAME SHKDEFTIIP VLVGALSESK EQEFGKLFSK YLADPSNLFV VSSDFCHWGQ RFRYSYYDES QGEIYRSIEH LDKMGMSIIE QLDPVSFSNY LKKYHNTICG RHPIGVLLNA ITELQKNGMN MSFSFLNYAQ SSQCRNWQDS SVSYAAGALT VH

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: MEMO1
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 36.4 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 50% glycerol, 5mM DTT, 300 mM NaCl, 2 mM EDTA
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human mediator of cell motility 1 His Protein

• C21orf19-like protein
• C2orf4DKFZp434I0135
• CGI-27
• FLJ25031
• HCV NS5A-transactivated protein 7
• Hepatitis C virus NS5A-transactivated protein 7
• mediator of cell motility 1
• Mediator of ErbB2-driven cell motility 1
• memo-1
• MEMOchromosome 2 open reading frame 4
• NS5ATP7
• protein MEMO1

Background

MEMO1 (Mediator of ErbB2-driven cell motility 1), also known as C2orf4 or NS5ATP7, belongs to the UPF0103 family. MEMO1 control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is required for breast carcinoma cell migration, suggesting an important role in tumorigenesis. Also, it controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. Recombinant human MEMO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: MEMO1