MED24 Antibody [DyLight 405]

• Reactivity: Hu, Mu, Rt, Ch
• Applications: WB, IP, KO
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 405

MED24 Antibody [DyLight 405] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 939 and 989 of human thyroid hormone receptor-associated protein complex 100 kDa component (mediator complex subunit 24 ) using the numbering given in entry NP_055630.2 (GeneID 986).
• Localization: Nuclear
• Predicted Species: Rat (100%), Chicken (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MED24
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Knockout Validated
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MED24 Antibody [DyLight 405]

• cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa
• CRSP100
• DRIP100CRSP complex subunit 4
• hTRAP100
• KIAA0130CRSP4
• mediator complex subunit 24ARC100
• MGC8748
• subunit 24 homolog
• thyroid hormone receptor associated protein 4
• Thyroid hormone receptor-associated protein 4
• Thyroid hormone receptor-associated protein complex 100 kDa component
• Trap100
• TRAP100THRAP4
• Vitamin D3 receptor-interacting protein complex 100 kDa component
• vitamin D3 receptor-interacting protein complex component DRIP100

Background

MED24 encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MED24