MCM5 Antibody

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Immunohistochemistry:[NBP3-29204]-Detection of human MCM5 by immunohistochemistry. Sample: FFPE section of human seminoma. Antibody: Affinity purified rabbit anti-MCM5.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MCM5 Antibody Summary

Description
Novus Biologicals Rabbit MCM5 Antibody (NBP3-29204) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Between 1 and 50
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MCM5
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-buffered Saline 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for MCM5 Antibody

  • CDC46 homolog
  • CDC46DNA replication licensing factor MCM5
  • EC 3.6.4.12
  • MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S.cerevisiae)
  • MCM5 minichromosome maintenance deficient 5, cell division cycle 46
  • MGC5315
  • minichromosome maintenance complex component 5
  • minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46)
  • minichromosome maintenance deficient 5 (cell division cycle 46)
  • P1-CDC46

Background

MCM5 (Mini Chromosome Maintenance protein-5) is involved in the control of DNA replication. MCM proteins have DNA dependent ATPase motifs in their central domain which is conserved from yeast to mammals. MCM proteins form a complex which exhibits ATPase and helicase activities. In G0 phase levels of MCM 2 and 5 are lower than that of MCM7 and 3 but increase as the cell enters G1/S phase of the cell cycle. It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MCM5