MAX binding protein Antibody

Western Blot: MAX binding protein Antibody [NBP1-32757] - Sample (30 ug of whole cell lysate)A: A431 B: HeLa7. 5% SDS PAGE, antibody diluted at 1:1000.

Product Discontinued

MAX binding protein Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human MNT. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Mouse (93%), Rat (94%), Bovine (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MNT
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 62 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for MAX binding protein Antibody

• BHLHD3
• bHLHd3Max-interacting protein
• Class D basic helix-loop-helix protein 3
• MAD6
• MAX binding protein
• MXD6
• Myc antagonist MNT
• Protein ROX
• ROXmax-binding protein MNT

Background

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for MAX binding protein Antibody (NBP1-32757)(1)

Publication using NBP1-32757

• Steinberger J, Robert F, Halle M et al. Tracing MYC Expression for Small Molecule Discovery Cell Chem Biol 2019-02-21 [PMID: 30880156] (WB, Human)

Bioinformatics

• Gene Symbol: MNT