MAX binding protein Products

Description

MNT, also known as MAX-binding protein MNT, is a 582 amino acid protein that is 62 kDa, has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth and represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Current research is being performed on several diseases and disorders including Miller-Dieker lissencephaly, Miller-Dieker syndrome, Williams-Beuren syndrome, tetanus neonatorum, rheumatic fever, lissencephaly, tetanus, cholestasis, rabies, medulloblastoma, lung cancer, neuroblastoma, and leukemia.

Bioinformatics

Entrez	4335 Human
Uniprot	NP_064706 Human
Product By Gene ID	4335
Alternate Names	BHLHD3 bHLHd3Max-interacting protein Class D basic helix-loop-helix protein 3 MAD6 MAX binding protein MXD6 Myc antagonist MNT Protein ROX ROXmax-binding protein MNT

Research Areas for MAX binding protein

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication