Recombinant Human MAVS Protein Summary
A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-540 of Human VISA full-length ORF
Source: Wheat Germ (in vitro)
Amino Acid Sequence:MPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFNTLQRRPGWVEYFIAALRGCELVDLADEVASVYESYQPRTSDRPPDPLEPPSLPAERPGPPTPAAAHSIPYNSCREKEPSYPMPVQETQAPESPGENSEQALQTLSPRAIPRNPDGGPLESSSDLAALSPLTSSGHQEKDTELGSTHTAGATSSLTPSRGPVSPSVSFQPLARSTPRASRLPGPTGSVVSTGTSFSSSSPGLASAGAAEGKQGAESDQAEPIICSSGAEAPANSLPSKVPTTLMPVNTVALKVPANPASVSTVPSKLPTSSKPPGAVPSNALTNPAPSKLPINSTRAGMVPSKVPTSMVLTKVSASTVPTDGSSRNEETPAAPTPAGATGGSSAWLDSSFENRGLGSELSKPGVLASQVDSPFSGCFEDLAISASTSLGMGPCHGPEENEYKSEGTFGIHVAENPSIQLLEGNPGPPADPDGGPRPQADRKFQEREVPCHRPSPGALWLQVAVTGVLVVTLLVVLYRRRLH
in vitro wheat germ expression system
|Details of Functionality
This protein is not active and should not be used for experiments requiring activity.
| Protein/Peptide Type
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human MAVS Protein
- CARD adapter inducing interferon beta
- CARD adapter inducing interferon-beta
- CARD adaptor inducing IFN-beta
- IFN-B promoter stimulator 1
- Interferon beta promoter stimulator protein 1
- interferon-beta promoter stimulator protein 1
- mitochondrial antiviral signaling protein
- mitochondrial antiviral-signaling protein
- mitochondrial viral signaling protein
- Putative NF-kappa-B-activating protein 031N
- virus-induced signaling adapter variant 1b
- virus-induced signaling adaptor variant 1a
- Virus-induced-signaling adapter
Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005 [PubMed 16239922]).[supplied by OMIM]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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Product General Protocols
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Molecular weight of MAVS?
- MAVS is a 540 aa protein with a predicted size of 56 kDa.
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