MAVS Antibody (Adri-1) - BSA Free

Western Blot: MAVS Antibody (Adri-1) - BSA Free [NBP2-80052] - Cardif is cleaved in liver of a patient infected by the hepatitis C virus. Protein extracts of liver biopsies from a patient with chronic hepatitis C (CHC) and as a control from a patient with alcoholic hepatitis (AH) were run on a SDS-gel and revealed with anti-Cardif (human), mAb (Adri-1) (Prod. No. NBP2-80052).

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC, IP
• Clone: Adri-1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

MAVS Antibody (Adri-1) - BSA Free Summary

• Description: Novus Biologicals Mouse MAVS Antibody (Adri-1) - BSA Free (NBP2-80052) is a monoclonal antibody validated for use in IHC, WB, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human MAVS (aa 160-450).
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAVS
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 10% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for MAVS Antibody (Adri-1) - BSA Free

• CARD adapter inducing interferon beta
• CARD adapter inducing interferon-beta
• CARD adaptor inducing IFN-beta
• Cardif
• DKFZp547C224
• DKFZp666M015
• FLJ27482
• IFN-B promoter stimulator 1
• Interferon beta promoter stimulator protein 1
• interferon-beta promoter stimulator protein 1
• IPS-1
• IPS-1FLJ41962
• IPS1MGC3260
• KIAA1271FLJ35386
• MAVS
• mitochondrial antiviral signaling protein
• mitochondrial antiviral-signaling protein
• mitochondrial viral signaling protein
• Putative NF-kappa-B-activating protein 031N
• virus-induced signaling adapter variant 1b
• virus-induced signaling adaptor variant 1a
• Virus-induced-signaling adapter
• VISA
• VISAFLJ38051

Background

Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for MAVS Antibody (NBP2-80052). (Showing 1 - 1 of 1 FAQ).

1. Molecular weight of MAVS?
   • MAVS is a 540 aa protein with a predicted size of 56 kDa.

Bioinformatics

• Gene Symbol: MAVS