MARK4 Antibody (OTI9B7) [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI9B7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

MARK4 Antibody (OTI9B7) [mFluor Violet 500 SE] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 390-467 of human MARK4(NP_113605) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MARK4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MARK4 Antibody (OTI9B7) [mFluor Violet 500 SE]

• EC 2.7.11
• EC 2.7.11.1
• FLJ12177
• FLJ90097
• KIAA1860MARK4L
• MAP/microtubule affinity-regulating kinase 4
• MAP/microtubule affinity-regulating kinase like 1
• MAP/microtubule affinity-regulating kinase-like 1
• MARK4 serine/threonine protein kinase
• MARKL1L
• MARKL1MARK4S
• Nbla00650

Background

MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MARK4