MARCO Antibody (PLK1) [DyLight 650]

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF, IHC, IP
• Clone: PLK1
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: DyLight 650

MARCO Antibody (PLK1) [DyLight 650] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.
• Specificity: This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples.
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: MARCO
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MARCO Antibody (PLK1) [DyLight 650]

• macrophage receptor with collagenous structureSCARA2Scavenger receptor class A member 2
• MARCO
• member 2
• SCARA2

Background

MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram negative and Gram positive bacteria via an extracellular, C terminal, scavenger receptor cysteine rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. MARCO may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MARCO