MAP4K2 Antibody [DyLight 594]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 594

MAP4K2 Antibody [DyLight 594] Summary

• Immunogen: mitogen-activated protein kinase kinase kinase kinase 2. (Uniprot# Q12851)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAP4K2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MAP4K2 Antibody [DyLight 594]

• B lymphocyte serine/threonine protein kinase
• B lymphocyte serine/threonine-protein kinase
• BL44
• EC 2.7.11
• EC 2.7.11.1
• GC kinase
• GCKMEK kinase kinase 2
• Germinal center kinase
• germinal centre kinase (GC kinase)
• MAP4K2
• MAPK/ERK kinase kinase kinase 2
• MEK kinase kinase 2
• MEKKK 2
• mitogen-activated protein kinase kinase kinase kinase 2
• Rab8 interacting protein
• Rab8-interacting protein
• RAB8IP
• RAB8IPMEKKK 2

Background

MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. MAP4K2 can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAP4K2