MALT1 Antibody (MALT1-C) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: MALT1-C
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

MALT1 Antibody (MALT1-C) [Alexa Fluor® 488] Summary

• Immunogen: Recombinant human MALT1
  Asp701-Thr808
  Accession # Q9UDY8
• Specificity: Detects human MALT1 in Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MALT1 Antibody (MALT1-C) [Alexa Fluor® 488]

• caspase-like protein
• DKFZp434L132
• EC 3.4.22.-
• MALT associated translocation
• MALT lymphoma-associated translocation
• MALT1
• MLT1
• MLTMALT-lymphoma associated translocation
• mucosa associated lymphoid tissue lymphoma translocation gene 1
• mucosa-associated lymphoid tissue lymphoma translocation protein 1
• Paracaspase

Background

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an approximately 91 kDa intracellular adaptor protein that forms a complex with Bcl10 and CARMA-1. The caspase-like domain of MALT1 cleaves Bcl10 and the NF kappa B inhibitor A20. This results in NF kappa B activation following signal transduction from cell surface ITAM-containing receptors including the T cell and B cell antigen receptors. Human MALT1 shares 87% aa sequence identity with mouse and rat MALT1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.