MAD4 Peptide

Product Discontinued

MAD4 Peptide Summary

• Description: A peptide to MXD4.
• Specificity: This peptide is specific for NB100-1117 only.
• Protein/Peptide Type: Peptide
• Gene: MXD4

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-1117.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Preservative: No Preservative

Alternate Names for MAD4 Peptide

• BHLHC12
• bHLHc12Max-interacting transcriptional repressor MAD4
• Class C basic helix-loop-helix protein 12
• Mad4 homolog
• MAD4Max-associated protein 4
• MAX dimerization protein 4
• Max dimerizer 4
• MST149
• MSTP149
• MXD4 MAX dimerization protein 4

Background

MAD4 is a member of the MAD gene family . The MAD genes encode basic helix loop helix leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MXD4