Species: Hu, Mu
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Description
MAD4 is a member of the MAD gene family . The MAD genes encode basic helix loop helix leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
10608 |
| Alternate Names |
- BHLHC12
- bHLHc12Max-interacting transcriptional repressor MAD4
- Class C basic helix-loop-helix protein 12
- Mad4 homolog
- MAD4Max-associated protein 4
- MAX dimerization protein 4
- Max dimerizer 4
- MST149
- MSTP149
- MXD4 MAX dimerization protein 4
|
Research Areas for MAD4
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
