LIV-1/Zip6 Antibody - BSA Free

Western Blot: LIV-1/Zip6 Antibody [NBP1-76503] - Mouse lung tissue lysate with LIV-1/Zip6 antibody at 1 ug/mL.

Immunohistochemistry-Paraffin: LIV-1/Zip6 Antibody [NBP1-76503] - Mouse lung tissue with ZIP6 antibody at 5 ug/mL.

Immunocytochemistry/ Immunofluorescence: LIV-1/Zip6 Antibody - BSA Free [NBP1-76503] - Immunofluorescence of LIV-1/Zip6 in mouse lung tissue with LIV-1/Zip6 antibody at 20 u/mL.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

LIV-1/Zip6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit LIV-1/Zip6 Antibody - BSA Free (NBP1-76503) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP6. The immunogen is located within amino acids 430 - 480 of ZIP6. Amino Acid Squence: FKDKKKKNQKKPENDD
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A6
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  LIV-1/Zip6 Peptide (NBP1-76503PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for LIV-1/Zip6 Antibody - BSA Free

• zinc transporter ZIP6
• LIV-1
• solute carrier family 39 (zinc transporter), member 6

Background

The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC39A6
• Uniprot:
  • NP_001092876(Human)