SLC39A10 Antibody - BSA Free

Western Blot: SLC39A10 Antibody [NBP1-76507] - Human spleen tissue lysate with SLC39A10 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: SLC39A10 Antibody - BSA Free [NBP1-76507] - Immunohistochemistry of SLC39A10 in human spleen tissue with SLC39A10 antibody at 2.5 u/mL.

Immunocytochemistry/ Immunofluorescence: SLC39A10 Antibody - BSA Free [NBP1-76507] - Immunofluorescence of SLC39A10 in human spleen tissue with SLC39A10 antibody at 20 u/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SLC39A10 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SLC39A10 Antibody - BSA Free (NBP1-76507) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-SLC39A10 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against an 18 amino acid synthetic peptide near the center of human ZIP10. The immunogen is located within amino acids 550 - 600 of ZIP10. Amino Acid Squence: AGTDDSVVSEDRLNETEL
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A10
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml.
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  SLC39A10 Peptide (NBP1-76507PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SLC39A10 Antibody - BSA Free

• DKFZp564L2123
• DKFZp781L10106
• FLJ90515
• KIAA1265
• LZT-Hs2
• MGC126565
• MGC138428
• solute carrier family 39 (metal ion transporter), member 10
• solute carrier family 39 (zinc transporter), member 10
• Solute carrier family 39 member 10
• zinc transporter ZIP10
• ZIP10
• ZIP-10
• Zrt- and Irt-like protein 10

Background

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC39A10 Antibody (NBP1-76507)(2)

Publications using NBP1-76507

• Ma S, Wang N, Liu R et al. ZIP10 is a negative determinant for anti-tumor effect of mannose in thyroid cancer by activating phosphate mannose isomerase Journal of experimental & clinical cancer research : CR 2021-12-09 [PMID: 34886901] (WB, Human)
• Loh KH, Stawski PS, Draycott AS et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell. 2016-08-25 [PMID: 27565350] (WB, Rat)

Bioinformatics

• Gene Symbol: SLC39A10
• Uniprot:
  • EDL99073(Rat)