SLC39A2/ZIP2 Antibody

Images

 
Western Blot: SLC39A2/ZIP2 Antibody [NBP1-76499] - Analysis of ZIP2 in (A) mouse and (B) rat brain tissue lysate with ZIP2 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: SLC39A2/ZIP2 Antibody [NBP1-76499] - Immunofluorescence of ZIP2 in human brain tissue with ZIP2 antibody at 20 ug/mL.
Immunohistochemistry: SLC39A2/ZIP2 Antibody [NBP1-76499] - SCL39A2 (1:200) from equine placenta. Heat based antigen retrieval using a EDTA based buffer for 10 min. Fetal part of the placenta displays stronger staining ...read more
Immunohistochemistry: SLC39A2/ZIP2 Antibody [NBP1-76499] - Immunohistochemistry of ZIP2 in human brain tissue with ZIP2 antibody at 2.5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, Rt, EqSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

SLC39A2/ZIP2 Antibody Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZIP2. The immunogen is located within amino acids 70 - 120 of ZIP2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC39A2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:200
Theoretical MW
32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
SLC39A2/ZIP2 Peptide (NBP1-76499PEP)
Reviewed Applications
Read 1 Review rated 5
using
NBP1-76499 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SLC39A2/ZIP2 Antibody

  • Eti-1
  • MGC119190
  • solute carrier family 39 (zinc transporter), member 2
  • Solute carrier family 39 member 2
  • zinc transporter ZIP2
  • ZIP-2
  • ZIP2hZIP2
  • Zrt- and Irt-like protein 2,6A1

Background

The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SLC39A2/ZIP2 Antibody (NBP1-76499) (0)

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Review for SLC39A2/ZIP2 Antibody (NBP1-76499) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Equine.

Reviews using NBP1-76499:
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IHC
(1)
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Images Ratings Applications Species Date Details
Immunohistochemistry SLC39A2/ZIP2 NBP1-76499
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reviewed by:
Claudia Klein
IHC Equine 06/09/2017
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Summary

ApplicationImmunohistochemistry
Sample TestedPlacental tissue
SpeciesEquine

Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SLC39A2/ZIP2 Antibody (NBP1-76499) (0)

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Secondary Antibodies

 

Isotype Controls

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Diseases for SLC39A2/ZIP2 Antibody (NBP1-76499)

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Recent Reviews

5
5
1
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2
0
1
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Claudia Klein
06/09/2017
Application: IHC
Species: Equine

Bioinformatics

Gene Symbol SLC39A2
Uniprot