LINGO-1 Antibody

Western Blot: LINGO-1 Antibody [NBP1-46335] - WB on brain lysates. Blocking with 1% LFDM for 30 min at RT; Primary antibody used at 1:2000 dilution incubated overnight at 4C.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: LYOPH

LINGO-1 Antibody Summary

• Description: Novus Biologicals Rabbit LINGO-1 Antibody (NBP1-46335) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide from c-terminal region of human LINGO-1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in many other species.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LINGO1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1 : 3000
  • Immunohistochemistry-Paraffin 1 : 3000
  • Western Blot 1:3000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.

Alternate Names for LINGO-1 Antibody

• FLJ14594
• LERN1
• LERN1UNQ201
• leucine rich repeat and Ig domain containing 1
• leucine rich repeat neuronal 6A
• Leucine-rich repeat and immunoglobilin domain-containing protein 1
• Leucine-rich repeat neuronal protein 1
• Leucine-rich repeat neuronal protein 6A
• LINGO1
• LINGO-1
• LRRN6A
• LRRN6Aleucine-rich repeat neuronal 6A
• MGC17422

Background

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible forsome inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator ofoligodentrocyte differentiation and axonal myelination

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LINGO1
• Entrez:
  • 84894(Human)