Lewis A Blood Group Antigen Antibody (7LE) [Allophycocyanin/Cy7]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow
Clone
7LE
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin/Cy7

Order Details

Lewis A Blood Group Antigen Antibody (7LE) [Allophycocyanin/Cy7] Summary

Immunogen
Mucins isolated from ovarian cyst fluid
Localization
Cell membrane, cytoplasmic and extracellular
Specificity
Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ABO
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Lewis A Blood Group Antigen Antibody (NBP2-50583APCCY7) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-50583AF350
Alexa Fluor 405 NBP2-50583AF405
Alexa Fluor 488 NBP2-50583AF488
Alexa Fluor 532 NBP2-50583AF532
Alexa Fluor 594 NBP2-50583AF594
Alexa Fluor 647 NBP2-50583AF647
Alexa Fluor 700 NBP2-50583AF700
Alexa Fluor 750 NBP2-50583AF750
Allophycocyanin NBP2-50583APC
Allophycocyanin/Cy7 NBP2-50583APCCY7
Biotin NBP2-50583B
DyLight 350 NBP2-50583UV
DyLight 405 NBP2-50583V
DyLight 488 NBP2-50583G
DyLight 550 NBP2-50583R
DyLight 594 NBP2-50583DL594
DyLight 650 NBP2-50583C
DyLight 680 NBP2-50583FR
DyLight 755 NBP2-50583IR
FITC NBP2-50583F
HRP NBP2-50583H
Janelia Fluor 549 NBP2-50583JF549
Janelia Fluor 646 NBP2-50583JF646
PE NBP2-50583PE
PE/Atto594 NBP2-50583PEATT594
PE/Cy5.5 NBP2-50583PECY55
PE/Cy7 NBP2-50583PECY7
PerCP NBP2-50583PCP

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Bioinformatics Tool for Lewis A Blood Group Antigen Antibody (NBP2-50583APCCY7)

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Bioinformatics

Gene Symbol ABO