Latent TGF-beta bp1 Antibody (35409) [Allophycocyanin]

PC-3 human prostate cancer cell line was stained with Mouse Anti-Human Latent TGF-beta bp1 APC-conjugated Monoclonal Antibody (Catalog # IC388A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Intracellular Molecules.

• Reactivity: Hu
• Applications: Flow
• Clone: 35409
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Latent TGF-beta bp1 Antibody (35409) [Allophycocyanin] Summary

• Immunogen: Human platelet-derived large latent TGF-beta 1 complex
• Specificity: Detects human LTBP-1 from the large latent TGF-beta 1 complex.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LTBP1
• Purity Statement: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Latent TGF-beta bp1 Antibody (35409) [Allophycocyanin]

• Latent TGFbeta bp1
• Latent TGF-beta bp1
• latent transforming growth factor beta binding protein 1
• latent-transforming growth factor beta-binding protein 1
• LTBP1
• LTBP-1
• MGC163161
• TGF-beta1-BP-1
• Transforming growth factor beta-1-binding protein 1

Background

TGF-beta  is synthesized as high molecular weight latent complexes. In platelets, the large latent TGF-beta 1 complex is composed of three components: mature TGF-beta 1 dimer; latency associated peptide; and a latent TGF-beta binding protein (LTBP) (1-3).The cDNAs for four binding proteins (LTBP-1, -2, -3 and -4) have now been cloned (4-5).

1. Miyazono, K. et al. (1991) EMBO J. 10:1091.
2. Moren, A. et al. (1994) J. Biol. Chem. 269:32469.
3. Yin, W. et al. (1995) J. Biol. Chem. 270:10147.
4. Kanzaki, T. et al. (1990) Cell 61:1051.
5. Saharinen, J. et al. (1998) J. Biol. Chem. 273:18459.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LTBP1